Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Building on Success: HEADSTRONG and The Inquiring Mind Transition to Jack.org
Ottawa, ON, September 9, 2026 – The Mental Health Commission of Canada is excited to announce that, effective September 8th, Jack.org will take over HEADSTRONG and The Inquiring Mind (TIM) to further increase the impact and growth of these programs…
Virtual Care Expansion and Physician Follow-Up Among Youth With First Mental Health Contact Through a Hospital: Population-Based Repeated Cross-Sectional Study
Background: Timely follow-up is crucial for youth whose first mental health contact is through a hospital; virtual care could facilitate this. Objective: This study aimed to examine the association between the significant expansion of virtual care in Ontario, Canada, and…
Video and App-Based Games for Youth Emotion Regulation: Scoping Review
Background: Emotion regulation (ER) is a transdiagnostic construct encompassing distinct strategies that can be used to encourage adaptive coping skills in support of youth’s (ages 10 to 24 years) mental health. ER is responsive to training and intervention, such as…
Autistic traits in unaffected first-degree relatives of individuals with schizophrenia and bipolar disorder: implications for shared familial neurodevelopmental vulnerability
BackgroundAutistic traits have increasingly been linked to schizophrenia (SCH) and bipolar disorder (BD) within a shared neurodevelopmental framework. However, whether these traits are similarly expressed in unaffected first-degree relatives of individuals with SCH and BD remains poorly understood.MethodsThis cross-sectional study…
Ketogenic therapy as a potential novel treatment approach for PTSD: an integrative review and proposed mechanistic model
BackgroundBrain and body metabolic disruptions have been suggested in several studies as a mechanism underlying posttraumatic stress disorder (PTSD). Therapies targeting metabolic pathways might provide new treatment options. This review explores the potential of ketogenic therapies, such as the ketogenic…
Telemedicine company offers GLP-1s for addiction
A CDC Covid restructuring, public trust in Fauci, and more health news from Morning Rounds
Investigating the DTI-ALPS index and its association with cognitive impairment in Alzheimer’s disease: a diffusion tensor imaging study
ObjectivesWith the global aging population, Alzheimer’s disease (AD) poses a major health challenge. The diffusion tensor image (DTI) analysis along the perivascular space (DTI-ALPS) index has emerged as a noninvasive imaging marker that indirectly reflects glymphatic function. However, its alterations…
Multimodal network alterations in diagnosis-age-defined early- and late-onset Alzheimer’s disease
IntroductionEarly-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD) may differ in large-scale network organization. We compared multimodal MRI markers of diagnosis-age-defined Alzheimer’s phenotypes.MethodsAlzheimer’s Disease Neuroimaging Initiative participants were classified by age at first recorded mild cognitive impairment or Alzheimer’s…
Usability, adherence and efficacy of coach-augmented dHealth cognitive behavioural therapy for insomnia in South African sexual assault survivors: a pilot study
IntroductionTreating sleep difficulties - a core symptom of posttraumatic stress disorder (PTSD) - can improve both sleep and broader psychiatric outcomes. Digital health (dHealth) applications offer a scalable way to deliver cognitive behavioural therapy for insomnia (CBT-i), particularly for trauma survivors…
Evaluation of the Acceptability, Feasibility and Exploration of the Efficacy of an Integrated Care Pathway CARIBOU
Conditions: Major Depressive Disorder (MDD) Interventions: Behavioral: CARIBOU Integrated Care Pathway; Behavioral: Treatment as Usual (TAU) Sponsors: Universidad de los Andes, Chile Not yet recruiting
Group Cognitive-Behavioral Intervention for Problematic Internet Use in Nepalese University Students
Conditions: Problematic Internet Use; Internet Addiction Interventions: Behavioral: Group Cognitive-Behavioral Intervention for Problematic Internet Use Sponsors: Tribhuvan University, Nepal Completed
iACT & iTBS for Sleep Quality in Depressed Adolescents
Conditions: Depressive Disorder; Sleep Disturbance Interventions: Behavioral: Internet-Delivered Acceptance and Commitment Therapy; Device: Intermittent Theta Burst Stimulation Sponsors: Central China Normal University Completed
From facing fears to experimental frontiers: immersive cinematic virtual reality environments as a catalyst for innovation in behavioral neuroscience
Virtual reality (VR) has gained traction in psychiatric research in exposure-based interventions for phobias, simulations of hallucinations in psychosis, and adaptations of cognitive-behavioral therapy. These applications demonstrate that emotionally immersive digital environments can meaningfully engage pathological processes in controlled settings.…
Pseudo-professional mechanism of collaborative mental health support in low-resource county-level contexts in China
China has made school-family-community collaboration a central policy direction for adolescent mental health, yet low-resource counties often lack the professional workforce, stable interorganizational arrangements, and non-stigmatizing pathways needed to reproduce an institutionalized service model. Existing research on task sharing shows…
Development and psychometric evaluation of the AI emotional engagement scale
BackgroundWith the increasing integration of artificial intelligence (AI) technologies into daily life, the underlying mechanisms of emotional interactions between users and AI have emerged as a critical research topic in the field of human-computer interaction (HCI). Existing studies have predominantly…
Differentiating the potential of continuum beliefs to reduce the public stigma of schizophrenia, depression, and alcohol dependence: associations with illness recognition and treatment recommendations
PurposePromoting continuum beliefs has been discussed as a strategy for stigma reduction. The current study examines associations of continuum beliefs with stigma aspects (stereotypes, emotions, and social distance) and mental health literacy (illness recognition and treatment recommendations).MethodsIn 2011, a sample…
The association between obstructive sleep apnea and total cerebral small vessel disease burden—Neurovascular insights of OSA
ObjectiveThis study was conducted to assess the relationship between the severity of obstructive sleep apnea (OSA) and the total burden score of cerebral small vessel disease (CSVD), global cerebral blood flow (CBF), and cognitive function. Moreover, the internal pathway through…
Follow-up attendance and documented reasons for non-attendance in child and adolescent mental health care: a retrospective analysis
BackgroundFailure to continue scheduled follow-up is a common challenge in child and adolescent mental health services and may reduce treatment effectiveness.ObjectiveThe present retrospective study aimed to examine demographic, clinical, and treatment-related characteristics associated with attendance at the last scheduled follow-up…
A Pragmatic SMART Study of Medication and CBT Sequencing in Pediatric Anxiety Disorders: A Randomized Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 9, Page 668-681, September 01, 2026.