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1120 results

A stacking machine learning model for identifying comorbid anxiety disorder in children and adolescents with functional abdominal pain disorders

ObjectiveComorbid anxiety disorder is common in children and adolescents with functional abdominal pain disorders, but clinically usable risk-stratification tools integrating abdominal pain, psychosocial, school-related, and family-level information remain limited.MethodsIn this observational predictive modeling study, children and adolescents aged 7–18 years…

Tags: Academic research, Anxiety

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Attitudes toward treating functional neurological disorders: psychological service provider perspectives

IntroductionFunctional neurological disorders (FND) are characterized by involuntary sensory, motor, and/or other seemingly neurological symptoms lacking expected medical explanation. Once diagnosed, patients often are referred to mental health providers for psychotherapy, which is effective in treating many FND symptom presentations…

Tags: Academic research, Mental health, Therapy, United States

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From single pathways to holistic networks: unraveling the multimechanistic actions of acupuncture in depression

Depression is a globally prevalent mental disorder; however, current pharmacological treatments are limited by a delayed onset of action and significant adverse effects. As a safe and effective non-pharmacological therapy, acupuncture demonstrates unique advantages in treating mild to moderate depression.…

Tags: Academic research, Depression, Medication, Mood and emotional regulation

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When support becomes dependence: conversational continuity and relational safety in human-AI interaction

BackgroundConversational artificial intelligence (AI) is increasingly used for emotional support, reflection, and consequential decision-making. Although conversational continuity may improve responsiveness, sustained interaction also exposes AI systems to their own prior relational language, potentially shaping how they respond when users become…

Tags: Academic research, Substance abuse, Substance use

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Positive–affective and negative–cognitive brain–behavior axes in clinical high risk for psychosis

Individuals at clinical high risk for psychosis (CHR) present with heterogeneous combinations of positive, negative, and affective symptoms, cognitive difficulties, and functional impairment. However, reproducible multivariate links between this multidomain phenotype and brain morphology remain limited. This study explored the…

Tags: Academic research, Reality testing and perceptual stability, Schizophrenia spectrum

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Rosie en Español, a Chatbot-Delivered Intervention for Spanish-Speaking, US-Based Latina Mothers: Pilot Randomized Controlled Trial

Background: Latina pregnant women and mothers of infants in the United States experience elevated risk for perinatal anxiety, stress, and depression alongside persistent barriers to culturally and linguistically responsive care. AI-powered digital health tools offer a potentially scalable approach to…

Tags: Academic research, Anxiety, Depression, Mental health, Mood and emotional regulation, United States

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What Living With OCD Really Feels Like

“I view having OCD like living inside a glass box while holding the keys to the door.” Adolfo Flores-Quilcate shares what rumination, diagnosis, and ERP have taught him — and why he believes healing is possible. The post What Living…

Tags: Academic research, Charity / nonprofit, Cognitive focus and executive control, Mental health, OCD, United States

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Microglia in the neurogenic niche: emerging roles of immunometabolism

Adult neurogenesis is dynamically regulated by the neurogenic niche, yet the mechanisms governing its remodeling are not fully elucidated. Current research has increasingly extended beyond the intrinsic properties of neural stem cells to consider the broader microenvironment in which neurogenesis…

Tags: Academic research, Depression, Mood and emotional regulation

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ADHD-related mental health and school impairments across educational stages: sex-specific patterns in Japanese youth

IntroductionWhile ADHD-related challenges are well-documented internationally, understanding of how these manifest across educational stages and sexes remains limited. This study examined mental health symptoms and school functioning in Japanese children with and without ADHD across elementary, junior high, and senior…

Tags: Academic research, ADHD, Anxiety, Cognitive focus and executive control, Mental health, Mood and emotional regulation

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Outcome indicators used in recovery college effectiveness studies: a scoping review

IntroductionRecovery Colleges (RCs) are educational, recovery-oriented approaches in mental health. Differences in evaluation purposes and settings may lead to diverse outcome indicators, making it important to map their use and supporting measurement evidence. This scoping review aimed to identify the…

Tags: Academic research, Healthcare provider, Mental health

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Psychopathy is a key to integrating dimensional personality disorder constructs and psychotherapy: toward a reformulation of personality and its disruption

While the conceptualization of personality disorder (PD) moves toward a dimensional approach, the broader adoption within clinical practice appears slow. The lack of a unifying framework in diagnostic classifications might explain this issue. Here, psychopathy, arguably the most pervasive and…

Tags: ASPD spectrum, Therapy

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Evaluating the PolarUs App in People With Bipolar Disorder

Conditions: Bipolar Disorder (BD); Quality of Life (QOL) Interventions: Device: PolarUs Mobile App Sponsors: University of British Columbia; Canadian Institutes of Health Research (CIHR) Not yet recruiting

Tags: Academic research, Bipolar, Canada, Health app

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Assisting Screening of Adolescent Depression With Large Language Models as Symptom Detectors: Algorithm Development and Validation

Background: Depression prevalence is rising in adolescents and young adults (ages 10-24 years). Traditional screening methods for depression, such as the Patient Health Questionnaire (PHQ-9), are particularly challenging for adolescents. AI has potential to help with this, but the scarcity…

Tags: Academic research, Depression, Healthcare provider, Mental health, Mood and emotional regulation, Sleep and arousal regulation

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Depressive symptoms and occupational correlates among psychiatric nurses in northern Jiangsu: an explanatory sequential mixed-methods study

BackgroundPsychiatric nurses manage aggression, interrupted recovery and emotionally demanding care. Surveys quantify distress but rarely show how these experiences accumulate during routine work.AimWe aimed to estimate the prevalence of a positive depressive-symptom screen among psychiatric nurses and to quantify its…

Tags: Academic research, Depression, Healthcare provider

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Psychiatric service dogs reduce loneliness and improve social functioning in adults with mental health conditions: a qualitative study from South Africa

IntroductionLoneliness and impaired social functioning are clinically significant features of mental illness. Psychiatric service dogs (PSDs) are individually trained to perform tasks that mitigate the functional impact of psychiatric disability and have been proposed as an intervention for loneliness and…

Tags: Academic research, Mental health

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Beyond diagnostic categories: transdiagnostic psychological mechanisms associated with suicidal ideation among university students: a systematic review (2021–2025)

IntroductionConventional diagnostic categories may not fully capture the psychological processes associated with suicidal ideation among university students. This systematic review synthesized recent evidence on candidate transdiagnostic psychological mechanisms, distinguishing ideation-specific findings from broader suicide-related outcomes.MethodsScopus, Web of Science, PubMed, and…

Tags: Academic research, Depression

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Simultaneous measurement of Midbrain and Striatal Dopamine in Schizophrenia using an agonist radiotracer

Imaging studies showing greater amphetamine-induced dopamine release in patients with schizophrenia (SCZ) compared to matched healthy controls (HC) have been repeatedly replicated, but these studies all used radiotracers that were dopamine D2 receptor antagonists. A more recent study using an…

Tags: Academic research, Fear and threat response, Medication, Motor and impulse regulation, Schizophrenia spectrum

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