Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Adapting the Sensory Environment to Reduce Stress in Children With Autism During Dental Visits
Conditions: Autism; Autism Disorders and Maternal Stress; Sensory Integration Disorder; Stress Biomarkers Interventions: Behavioral: Sensory-Adapted Dental Environment Sponsors: Jagiellonian University Active, not recruiting
The application of transcranial magnetic stimulation in treatment-resistant depression: insights from omics
Treatment-resistant depression (TRD) is a refractory form of major depressive disorder (MDD) for which conventional antidepressant strategies are often insufficient. Transcranial magnetic stimulation (TMS) has demonstrated clinical efficacy in TRD, but its biological mechanisms remain incompletely understood. This narrative review…
Effect of soft Chinese martial arts on depressive symptoms among college students: a systematic review and meta-analysis
ObjectivesMental health problems are a growing concern among college students worldwide. While exercise is a proven mental health intervention, a quantitative synthesis on the effects of soft Chinese martial arts, as a unique mind-body practice, on depression in this specific…
Acupuncture–antidepressant combinations for clinically diagnosed depressive disorders in China: a systematic review and network meta-analysis
IntroductionTo evaluate the short-term efficacy and safety of acupuncture–antidepressant combinations for clinically diagnosed depressive disorders among participants recruited in China using a network meta-analysis.MethodsPubMed, Embase, the Cochrane Library, Web of Science, CNKI, and Wanfang were searched from inception to February…
[Comment] Preventing perinatal depression relapse
Mental health conditions are a leading cause of pregnancy-related deaths in the USA, affecting at least 20% of individuals in pregnancy and postpartum.1 Psychiatric relapse and emergencies in the perinatal period are disproportionately greater for women with a history of…
The BELONG Study: Black Equality in OCD NeuroGenomics
By Boris Litvin, MA, Matthew Riello, Andrew Marshall, PhD, Emily Rodriguez, MS, MSc, Martha Falkenstein, PhD, and Alexander Rosenberg One word appears more and more in the news surrounding mental... Read more » The post The BELONG Study: Black Equality…
Targeted Brain Ultrasound Could Help Relieve Schizophrenia Symptoms
Research suggests a type of low-intensity targeted ultrasound could be an effective treatment for delusions in people with schizophrenia or schizoaffective disorder. The post Targeted Brain Ultrasound Could Help Relieve Schizophrenia Symptoms appeared first on Inside Precision Medicine.
Diagnostic and predictive value of structural and high-order functional brain topology in major depressive disorder
BackgroundConventional neuroimaging analyses for major depressive disorder (MDD) predominantly construct brain networks based solely on pairwise regional functional couplings. Accumulating microscale neuroscientific evidence highlights the essential role of higher-order interactions (HOIs, interactions among three or more brain nodes) in capturing…
Development and contextual adaptation of the first national clinical practice guideline for autism spectrum disorder in children and adolescents in Tunisia
IntroductionAutism Spectrum Disorder (ASD) is a neurodevelopmental condition requiring long-term, coordinated, and multidisciplinary care. Although ASD services in Tunisia have improved, coordination across health, education, and social sectors remains limited, affecting equitable access and continuity of care. This study aimed…
Developing Virtual Reality Programs to Address Social Skills Deficits in Youth With ADHD
Conditions: Attention-Deficit/Hyperactivity Disorder (ADHD) Interventions: Device: VIP Suite Sponsors: Indiana University; National Institute of Mental Health (NIMH) Not yet recruiting
Multi-Omics Genetic Investigation Strategies to Enhance the Diagnostic Workflow for Rare Diseases
Conditions: Neurodevelopmental Disorders; Intellectual Disability; Autism Spectrum Disorder; Genetic Diseases, Inborn Sponsors: Istituto Giannina Gaslini; Ministry of Health, Italy Recruiting
Evaluating the Effectiveness of an Adapted-Dialectical Behavior Therapy (A-DBT)
Conditions: Treatment Interventions: Behavioral: Adapted Dialectical Behavioral Therapy (A-DBT) Sponsors: International Islamic University, Islamabad Completed
Incorporating Data From Text Messages and Email Into Psychotherapy: Randomized Controlled Trial
Background: As digital communication becomes central to daily life, psychotherapy increasingly has access to patients’ electronic media data. Although digital phenotyping has been widely studied, less is known about whether incorporating personal communication data, such as text messages, improves clinical…
Symptom Trajectories and Attendance in Face-to-Face and Online Psychiatric Follow-Up for Major Depressive Disorder and Anxiety Symptoms: Prospective Observational Cohort Study
Background: Major depressive disorder is a leading cause of disability, and access to specialist psychiatric follow-up remains limited in many settings. Telepsychiatry may reduce logistical barriers to care, but data on video-based follow-up under routine outpatient conditions in Türkiye are…
Characterizing Behavioral Engagement in Smartphone Cognitive Behavioral Therapy for Obsessive Compulsive Disorder: Secondary Analysis of a Randomized Controlled Trial
Background: Digital mental health interventions (DMHIs) are increasingly popular for their ability to disseminate evidence-based treatments in a scalable, accessible way. Engagement with digital treatments is critical for effectiveness but remains poorly defined and measured. Most studies rely on subjective…
Bridgedd, a Health Care Staff–Facing Community Resource Navigation Tool for an Urban Safety-Net Hospital: Cross-Sectional Formative Pilot Study
Background: Health care professionals in safety-net settings often rely on lengthy and inconsistently maintained community health resource lists when connecting patients with services. Bridgedd is a health care staff–facing web application designed to generate geographically and categorically filtered community resources…
“There is a Place for it”—Practitioners’ Perspectives on Situated Ethical Acceptability of AI Technologies for Mental Health Practice: Qualitative Study
Background: Design research on AI technologies for mental health has expanded rapidly, yet existing work has largely focused on practitioners’ perspectives within isolated therapeutic stages or specific services. As a result, there is limited understanding of how practitioners view the…
What Is Guanfacine?
Guanfacine is a non-stimulant medication that is FDA-approved to treat ADHD in children and teens. It can also be used off label to treat tic disorders and symptoms of autism. Guanfacine is not as powerful in reducing ADHD symptoms as…
In-person UCLA-PEERS® program for adolescents with autism spectrum disorder in Italy: study protocol for a pilot and feasibility randomized controlled trial with pragmatic features and exploratory EEG markers of treatment response
BackgroundAdolescents with Autism Spectrum Disorder (ASD) Level 1 frequently experience persistent difficulties in peer relationships and social functioning that become more evident as social demands increase. Group-based social skills trainings represent a key evidence-based intervention for this population, yet its…
The association between cognitive disengagement syndrome and language in children with attention-deficit/hyperactivity disorder
AimThis study aims to explore the association between cognitive disengagement syndrome (CDS) and three aspects of language (narrative coherence, core language, and pragmatic language) in children with ADHD, and to examine whether these associations differ from those observed in neurotypical…