Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Usability, adherence and efficacy of coach-augmented dHealth cognitive behavioural therapy for insomnia in South African sexual assault survivors: a pilot study
IntroductionTreating sleep difficulties - a core symptom of posttraumatic stress disorder (PTSD) - can improve both sleep and broader psychiatric outcomes. Digital health (dHealth) applications offer a scalable way to deliver cognitive behavioural therapy for insomnia (CBT-i), particularly for trauma survivors…
Evaluation of the Acceptability, Feasibility and Exploration of the Efficacy of an Integrated Care Pathway CARIBOU
Conditions: Major Depressive Disorder (MDD) Interventions: Behavioral: CARIBOU Integrated Care Pathway; Behavioral: Treatment as Usual (TAU) Sponsors: Universidad de los Andes, Chile Not yet recruiting
Group Cognitive-Behavioral Intervention for Problematic Internet Use in Nepalese University Students
Conditions: Problematic Internet Use; Internet Addiction Interventions: Behavioral: Group Cognitive-Behavioral Intervention for Problematic Internet Use Sponsors: Tribhuvan University, Nepal Completed
iACT & iTBS for Sleep Quality in Depressed Adolescents
Conditions: Depressive Disorder; Sleep Disturbance Interventions: Behavioral: Internet-Delivered Acceptance and Commitment Therapy; Device: Intermittent Theta Burst Stimulation Sponsors: Central China Normal University Completed
Pseudo-professional mechanism of collaborative mental health support in low-resource county-level contexts in China
China has made school-family-community collaboration a central policy direction for adolescent mental health, yet low-resource counties often lack the professional workforce, stable interorganizational arrangements, and non-stigmatizing pathways needed to reproduce an institutionalized service model. Existing research on task sharing shows…
From facing fears to experimental frontiers: immersive cinematic virtual reality environments as a catalyst for innovation in behavioral neuroscience
Virtual reality (VR) has gained traction in psychiatric research in exposure-based interventions for phobias, simulations of hallucinations in psychosis, and adaptations of cognitive-behavioral therapy. These applications demonstrate that emotionally immersive digital environments can meaningfully engage pathological processes in controlled settings.…
Development and psychometric evaluation of the AI emotional engagement scale
BackgroundWith the increasing integration of artificial intelligence (AI) technologies into daily life, the underlying mechanisms of emotional interactions between users and AI have emerged as a critical research topic in the field of human-computer interaction (HCI). Existing studies have predominantly…
Differentiating the potential of continuum beliefs to reduce the public stigma of schizophrenia, depression, and alcohol dependence: associations with illness recognition and treatment recommendations
PurposePromoting continuum beliefs has been discussed as a strategy for stigma reduction. The current study examines associations of continuum beliefs with stigma aspects (stereotypes, emotions, and social distance) and mental health literacy (illness recognition and treatment recommendations).MethodsIn 2011, a sample…
The association between obstructive sleep apnea and total cerebral small vessel disease burden—Neurovascular insights of OSA
ObjectiveThis study was conducted to assess the relationship between the severity of obstructive sleep apnea (OSA) and the total burden score of cerebral small vessel disease (CSVD), global cerebral blood flow (CBF), and cognitive function. Moreover, the internal pathway through…
Follow-up attendance and documented reasons for non-attendance in child and adolescent mental health care: a retrospective analysis
BackgroundFailure to continue scheduled follow-up is a common challenge in child and adolescent mental health services and may reduce treatment effectiveness.ObjectiveThe present retrospective study aimed to examine demographic, clinical, and treatment-related characteristics associated with attendance at the last scheduled follow-up…
A Pragmatic SMART Study of Medication and CBT Sequencing in Pediatric Anxiety Disorders: A Randomized Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 9, Page 668-681, September 01, 2026.
Convergence of TMS Sites and Lesion Locations Associated With Nicotine Addiction Improvement on a Common Brain Circuit
American Journal of Psychiatry, Volume 183, Issue 9, Page 646-656, September 01, 2026.
Dynamic Relationships Between Estrogen Fluctuations, Sleep, and Psychiatric Complexity Among Adolescent Females With ADHD: A Pilot Study
Conditions: ADHD Sponsors: Duke University Not yet recruiting
This Study Will Evaluate Cardiorespiratory and Muscular Fitness to Examine Associations With Anthropometric Characteristics and Other Indicators of Cardiometabolic Risk Among Patients With or Without Autism Spectrum Disorder
Conditions: Autism Spectrum Disorder (ASD); Cardiometabolic Health Indicators; Cardiometabolic Risk Factors; Metabolic Syndrome; Prediabetes Sponsors: University of Virginia Recruiting
Remotely Supervised, Home-Based Transcranial Direct Current Stimulation for Major Depressive Disorder: Systematic Review and Meta-Analysis
Background: Major depressive disorder affects over 280 million people worldwide, and access to effective treatment remains limited. Transcranial direct current stimulation (tDCS) is a noninvasive option, and portable devices now allow for home-based delivery under varying degrees of remote supervision.…
Adult ADHD Symptoms, Depression, Anxiety, and Academic Performance in Medical Students
Conditions: Attention Deficit Hyperactivity Disorder; Depression; Anxiety; Academic Performance Sponsors: Assiut University Not yet recruiting
Executive Function Training Program for Children With ASD
Conditions: Autism Spectrum Disorder Interventions: Behavioral: Executive Function Training Program Sponsors: Seoul National University Bundang Hospital Active, not recruiting
Comparative Efficacy of Cognitive Behavioral and Mindfulness Therapies in Reducing Post-Traumatic Stress Disorder Among Interpersonal Violence Survivors
Conditions: Post-traumatic Stress Disorder (PTSD); Post-Traumatic Stress Disorder Interventions: Behavioral: Cognitive Behavioral Therapy (CBT); Behavioral: Mindfulness-Based Therapy (MBT); Behavioral: Psychoeducation Sponsors: GIFT University Active, not recruiting
Gene alteration in human brain suggests genetic and epigenetic roots of major depression
Nature Medicine, Published online: 03 September 2026; doi:10.1038/s41591-026-04682-2A large, multimodal molecular characterization of the adult human hippocampus provides evidence for sustained neurogenesis and identifies a stalled neurogenic process in major depressive disorder (MDD). Cell- and circuit-specific genetic, epigenetic, stress, immune,…