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1120 results

Global economic burden of depression in 154 countries from 2025 to 2050

Nature Medicine, Published online: 28 July 2026; doi:10.1038/s41591-026-04548-7A macroeconomic modeling analysis across 154 countries estimates that depression will impose a US$12 trillion global economic burden between 2025 and 2050, equivalent to around 0.5% of the annual global GDP.

Tags: Academic research, Depression, Medication, Mood and emotional regulation

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Structuring Digital Mental Health Care Navigation: Co-Design Nominal Group Technique Study to Develop the MChart Definition and Typology of the Characteristics of Digital Mental Health Care Navigation Tools

Background: Australia’s mental health care system has been characterized by complexity and fragmentation, as highlighted by numerous reports, commissions, and inquiries. In response, digital mental health care navigation tools have emerged as a promising solution to help individuals locate appropriate…

Tags: Academic research, Australia, Mental health

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Mobility Patterns and Mental Health During the COVID-19 Pandemic: Longitudinal Observational Study Using Smartphone Mobility Data

Background: The COVID-19 pandemic disrupted mobility globally, but its mental health implications remain difficult to characterize because most studies relied on lockdown status, population-level mobility indicators, or self-reported mobility. These approaches may miss individual differences in actual movement patterns and…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation, PTSD

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MapLight’s Schizophrenia Candidate Has Mixed Results at Phase II

MapLight's schizophrenia candidate drug, a possible Cobenfy competitor, has succeeded at Phase II—although only at the higher dose tested in the trial. The post MapLight’s Schizophrenia Candidate Has Mixed Results at Phase II appeared first on Inside Precision Medicine.

Tags: Academic research, Cognitive focus and executive control, Medication, Reality testing and perceptual stability, Schizophrenia spectrum, United States

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Synaptic mechanisms for differential severity of social preference deficits in male and female mice induced by diminished activity-dependent BDNF

Males are more commonly diagnosed with autism spectrum disorder (ASD) than females with a ratio of about 4–1. However, the neural mechanisms underlying the sex differences in ASD are unknown. Social deficits are the core symptoms of patients with ASD.…

Tags: Academic research, Autism, Cognitive focus and executive control, Mood and emotional regulation

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Historical trauma as a contributor to postpartum depression among Indigenous mothers

IntroductionPostpartum depression (PPD) is a significant public health concern. Moreover, research suggests that American Indian/Alaskan Native (AI/AN) mothers experience postpartum depression at higher rates than the general population (Heck, 2021; Ko et al., 2017). As a result, understanding the potential…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation, United States

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Immersive wearable virtual reality for autism: a systematic review of current evidence

IntroductionImmersive and wearable virtual reality (VR) is an emerging technology with growing potential to support assessment and intervention ifor autistic people. The methodological heterogeneity of existing studies limits the interpretation and generalization of current evidence.MethodsA systematic review with a narrative…

Tags: Academic research, Autism, Cognitive focus and executive control, Medical device

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Resting-state functional connectivity of the sensorimotor network in medication-naïve Chinese children with ADHD: cross-sectional associations with hyperactivity/impulsivity and executive function

BackgroundAttention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder, often—but not always—characterized by inattention, hyperactivity/impulsivity, and deficits in executive functions (EFs); some individuals may also exhibit sensorimotor dysfunction. While SMN dysfunction has been implicated in ADHD, the patterns of SMN functional…

Tags: Academic research, ADHD, Cognitive focus and executive control, Medication, Mental health, Sensory processing

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Sexuality and Relationship Education for Autistic Adults: Our Love, Our Style

Conditions: Autism Spectrum Disorder (ASD) Interventions: Behavioral: Web-Based Sex and Relationship Education; Behavioral: Group Coaching Sessions; Behavioral: Individual Coaching Sponsors: Ewha Womans University; National Research Foundation of Korea; So Hyun "Sophy" Kim, Associate Professor, Korea University Active, not recruiting

Tags: Academic research, Autism, Clinical trial

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Clinical Outcomes and Predictors of Improvement With Virtual Behavioral Health Care for Gambling Disorder: Retrospective Cohort Study

Background: Gambling disorder is associated with substantial psychiatric and functional burden, yet few individuals receive treatment. Limited real-world evidence exists evaluating outcomes of virtually delivered behavioral health care for gambling disorder, particularly among clinically complex patients. Objective: The purpose of…

Tags: Academic research, ADHD, Cognitive focus and executive control, Depression, Mental health, Mood and emotional regulation

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The associations between emotional neglect and positive mental health: the mediating role of stress-is-enhancing mindset and the moderating role of stress-is-debilitating mindset

ObjectiveThis study aimed to investigate the associations among emotional neglect (EN), stress-is-enhancing mindset (SIEM), stress-is-debilitating mindset (SIDM), and positive mental health (PMH).MethodsThe cross-sectional survey was employed in this study. A sample of 2150 college students (826 males) completed the emotional…

Tags: Academic research, Mental health

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Cross-national comparisons of adolescent mental health and suicidality in the Middle East: a cross-sectional secondary analysis of the global school-based student health survey

BackgroundAdolescent mental health and suicidality represent growing global public health concerns, yet comparative evidence from the Middle East remains limited. This study examined the prevalence and correlates of psychological distress and suicidal behaviors among adolescents across Middle Eastern countries using…

Tags: Academic research, Anxiety, Mental health

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NeuroCon-AutismNet: a privacy-preserving multimodal framework toward autism screening via diffusion-regularized EEG biomarkers and empathy-aware multilingual dialogue

IntroductionAutism Spectrum Disorder (ASD) screening requires multimodal biomarkers to capture the heterogeneous neurological and behavioral phenotypes. Current screening approaches remain siloed across EEG analysis and conversational assessment, limiting integrated diagnostic architecture. Privacy-preserving machine learning frameworks for mental health screening are…

Tags: Academic research, Autism, Biomarker, Mental health, Social and attachment drive

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Big Five personality profiles, self-reported distress, and resilience resources among adults in Italy after the acute COVID-19 emergency: a cross-sectional cluster-analytic study

IntroductionPsychological recovery after the acute COVID-19 emergency has been uneven, and brief non-diagnostic markers that stratify vulnerability may support public mental health monitoring. We examined whether person-centered Big Five profiles differentiated self-reported distress and resilience resources among adults living in…

Tags: Academic research, Anxiety, Depression, Mental health

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INTEGRATING EXPOSURE AND RESPONSE PREVENTION AND HABIT REVERSAL TECHNIQUES TO TREAT A TOURETTIC SUBTYPE OF OBSESSIVE-COMPULSIVE DISORDER (TOURETTIC OCD).

Conditions: Obsessive - Compulsive Disorder; Tic Disorder, Chronic Motor or Vocal; Tic Disorders; Tic Disorder, Combined Vocal and Multiple Motor; Tourette Disease; Tourette Disorder; Tourettes Syndrome; Gilles de la Tourette Syndrome Interventions: Behavioral: Exposure and Response Prevention (ERP); Behavioral: Habit…

Tags: Body-focused and impulse habits, Clinical trial, Motor and impulse regulation, OCD, Psychoeducation program, Tic & Tourette, United Kingdom

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