Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Case Report: Recurrent pathogenic mutation c.110G>A in DHDDS gene
Recent studies have demonstrated the close association of mutations in the dehydrodolichyl diphosphate synthase (DHDDS) gene with neurodevelopmental disorders and the onset of epilepsy. This report describes a female patient harboring a de novo heterozygous variant c.110G>A (p.Arg37His) in the…
Smartphone App–Delivered Mindfulness-Based Intervention for Concussion in Adolescents (MBI-4-mTBI): Feasibility Randomized Controlled Trial
Background: Persisting symptoms affect about one-third of youth following concussion. Mental health history, distress, and coping style are key predictors of prolonged recovery. Early and scalable psychological interventions, such as mindfulness-based intervention (MBI) delivered via smartphones, may improve patients’ ability…
Surf Therapy: A Powerful Low-Intensity Approach in Global Youth Mental Health Care
By Mai El Shoush, Partnerships Campaign Manager, Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute In Conversation with Waves for Change The world’s oceans have long been profound forces that shape…
Steroid receptor coactivator-1: integrating steroid hormone signals to regulate brain function and disease
Steroid receptor coactivator-1 (SRC-1), also known as nuclear receptor coactivator-1 (NCOA1), represents the first identified member of the p160 nuclear receptor coactivator family and plays a pivotal role in integrating steroid hormone signals, regulating gene transcription, and maintaining neural homeostasis…
The correlation between phubbing and depression anxiety stress of first-year medical students: the mediating role of sedentary behavior
BackgroundFreshmen often experience challenges when adjusting from high school to college, which may elevate levels of depression, anxiety, and stress. This phenomenon is particularly pronounced in medical schools, where the overall academic atmosphere is widely regarded as exceptionally demanding and…
Autonomic nervous system reactions to secondary exposure to disaster-related imagery
AimThis study investigated how disaster-related imagery affects emotional and autonomic nervous system (ANS) responses, using heart rate (HR) and heart rate variability (HRV), in individuals with indirect exposure to the 2011 Great East Japan Earthquake (GEJE).MethodsThirty-six healthy adults who had…
The connection between periods and mental health
Plans to oust Makary, a looming Supreme Court deadline on mifepristone, and other health news from Morning Rounds
Calming Minds Study
Conditions: Anxiety; Anxiety Depression; Worry; Depression; Rumination - Thoughts Interventions: Behavioral: Be Specific; Behavioral: Be Kind; Behavioral: Be Present; Behavioral: Break Habit; Behavioral: Psychoeducation Sponsors: University of California, Los Angeles; University of Exeter Not yet recruiting
Phenotype, Genetics, and Interpretation: Further Considerations on Atypical Depression
We read with great interest the recent article by Shin et al. (1). The authors leveraged the substantial Australian Genetics of Depression Study (AGDS) cohort to provide compelling evidence for the clinical and biological validity of the atypical depression subtype.…
Comorbidity alters the genetic relationship between anxiety disorders and major depression
The extensive genetic overlap between anxiety disorders (ANX) and major depression (MD) may partly reflect inclusion of comorbid cases in genome-wide association studies (GWAS). We investigated this genetic relationship between ANX and MD with and without mutual comorbidity.
What Is Traumatic Separation?
You may have a memory of being separated from a parent when you were a child, even just for a few minutes. Maybe you lost them in a crowd or wandered a little too far at the store and felt…
Two-year longitudinal neuropsychological monitoring after unilateral and staged bilateral subthalamic nucleus deep brain stimulation
IntroductionDeep brain stimulation (DBS) is an increasingly popular therapeutic method for treating motor symptoms in Parkinson’s disease, but its impact on non-motor symptoms in long-term follow-up remains debated.MethodThe primary objective of this study was to monitor the cognitive functioning, mood,…
Can exercise combined with transcranial direct current stimulation improve cognitive function in older adults? A systematic review and meta-analysis
ObjectiveThis study investigated whether combining exercise with transcranial direct current stimulation (tDCS) improves overall cognition, memory, and executive function in older adults.MethodsFollowing PRISMA guidelines, we systematically searched databases including PubMed, Web of Science, CNKI, and Wan Fang for randomized controlled…
Computer-based tree drawing test in adolescents and adults with depression
ObjectiveTo evaluate the value of the computer-based Tree Drawing Test in the auxiliary diagnosis of depressive disorders and to analyze the differences in the performance of adolescent and adult depression patients in the Tree Drawing Projection Test.MethodsThis study was conducted…
Extended Group Written Exposure Therapy for Comorbid PTSD and BPD (Traits)
Conditions: Posttraumatic Stress Disorder (PTSD); Borderline Personality Disorder (BPD) Interventions: Behavioral: Group Written Exposure Therapy Sponsors: St. Joseph's Healthcare Hamilton Not yet recruiting
Reestablishing Normal Gut-brain Interaction in Anorexia Nervose With Normal Gut Microbiota
Conditions: Anorexia Nervosa Interventions: Biological: Psychotherapy as usual combined with single dose normal gut microbiota; Other: Psychotherapy treatment as usual (TAU) Sponsors: Haukeland University Hospital; The Dam Foundation Not yet recruiting
Barriers and Facilitators in the Implementation of the Systematic Medical Appraisal, Referral, and Treatment (SMART) Mental Health Digital Intervention in Rural India: Mixed Methods Process Evaluation Study
Background: An estimated 150 million people have mental health care needs in India, but only 15% are able to access care. Depression and anxiety contribute to a large proportion of mental morbidity. The Systematic Medical Appraisal, Referral, and Treatment (SMART)…
Digital Therapeutic Content for Substance Use Disorder Treatment: Development and Evaluation Study
Background: Substance use disorders (SUDs) are a major public health concern, contributing to significant individual and societal costs. Despite this, the uptake of evidence-based pharmacologic and behavioral interventions remains limited. The digital delivery of SUD treatment has emerged as a…
Oral Small-Molecule GLP-1s Linked to Deep Brain Activity and Reduced Cravings in Mice
New findings in mice suggest that oral small-molecule GLP-1 drugs may directly influence deep brain pathways involved in desire, revealing how these therapies reduce cravings and food-seeking behavior. The post Oral Small-Molecule GLP-1s Linked to Deep Brain Activity and Reduced…
Autism Screening Proposed for Children with Epilepsy
Children with epilepsy should be screened for developmental concerns, following a study suggesting they are up to 10 times more likely than others to have autism. The post Autism Screening Proposed for Children with Epilepsy appeared first on Inside Precision…