Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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PMAT enhances sexual dimorphism of fear behaviors and facilitates female mice’s generalized contextual fear extinction
Enhanced signaling of dopamine and/or serotonin during highly arousing situations can be reduced in part by monoamine transporters, such as plasma membrane monoamine transporter (PMAT, Slc29a4). An absence of selective pharmacological inhibitors means genetically modified mice constitutively deficient in PMAT…
Identifying clinical features associated with electroconvulsive therapy response in adolescents with major depressive disorder using machine learning
BackgroundElectroconvulsive therapy (ECT) is an effective treatment for adolescent major depressive disorder (MDD), but its efficacy varies. This study utilized machine learning (ML) to identify baseline clinical factors associated with poor ECT response.MethodsWe retrospectively enrolled 503 adolescent MDD patients. A…
A two-decade bibliometric analysis (2004–2024) of parental factors in the context of internet gaming disorder research
ObjectiveThis is the first targeted bibliometric analysis which explores the development of scientific production on the relationship between parenting and Internet Gaming Disorder (IGD) over twenty years, emphasizing the central role of the family context in the etiology and maintenance…
[Articles] Who receives psychiatry-focused pharmacogenomic testing, and is it associated with prescribing patterns and acute care utilisation in depression? Real-world evidence from a large health system
In routine clinical practice, PGx testing is preferentially used in youth and adults with clinically complex histories and is associated with shifts in antidepressant prescribing patterns. Exploratory findings suggest hypothesis-generating signals of reduced psychiatric ED utilisation among patients with higher…
Noise, air pollution exposure and attention-deficit/hyperactivity disorder: a meta-analysis
ObjectiveThis meta-analysis evaluated the associations between noise exposure, air pollutants, and attention-deficit/hyperactivity disorder (ADHD) in children, aiming to inform future prevention strategies.MethodsStudies were systematically retrieved from CNKI, Wanfang, PubMed, Web of Science, Embase, and the Cochrane Library, covering publications from…
At-Home Blood Test Screens for Early Dementia
A simple, at-home blood test used together with online cognitive tests can spot early dementia, identifying people at greatest risk and potentially acting as a useful triage resource in remote settings. The post At-Home Blood Test Screens for Early Dementia…
Comparing Usual Care With Coordinated Clinician and Patient Use of Mobile Technology in Primary Care for Patients With Major Depressive Disorder: Practice-Based Pilot Study
Background: Major depressive disorder (MDD) affects millions of Americans each year and is often diagnosed and treated in primary care. Evidence shows that self-management techniques, shared decision-making (SDM), and goal setting are effective strategies for managing MDD, but the required…
“Failure to Launch” Syndrome: How to Stop Enabling Your Grown Child
When Zeke was in high school, he struggled with anxiety and substance use problems, and he left college after the first semester. Now 25, he is living at home, and his mom Carol is frustrated. While she’s pushed him to…
Biomarkers of ASD/ADHD and Factors Affecting Anxiety and Depression in Children and Young Adults
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity; Autism Spectrum Disorder (ASD); Developmental Coordination Disorder (DCD) Sponsors: University of Exeter; University of Southampton; University of Dublin, Trinity College; Carol Davila University of Medicine and Pharmacy; Jimma University; FUNDACION PARA LA…
Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT)
Conditions: Borderline Personality Disorder (BPD); Treatment-Resistant Major Depressive Disorder; Treatment-resistant Bipolar Depression; Major Depressive Disorder (MDD); Bipolar Disorder (BD); Bipolar Disorder I or II; Suicidal Ideation Interventions: Drug: Ketamine Hydrochloride; Drug: Midazolam Hydrochloride; Behavioral: Dialectical Behavioral Therapy (DBT) Sponsors: Joshua…
Personalized fMRI-Guided TMS Targeting the Threat Neurocircuitry in PTSD: A Randomized Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 5, Page 343-354, May 01, 2026.
Anxiety and Depression Associated With the Dependent Use of Generative AI in Medical Students: Cross-Sectional Study
Background: The growing integration of artificial intelligence (AI) in higher education has transformed learning processes but also raised concerns about potential mental health risks. Medical students represent a particularly vulnerable group due to high academic stress and increasing reliance on…
Psilocybin-Induced Brain Changes May Explain Therapeutic Effects
The results of a study carried out in human volunteers given a single dose of psilocybin link changes in brain entropy to insight and suggest that the psychedelic trip itself is important to the drug’s longer term therapeutic effects. The…
Statement on Mental Health and Access to Evidence-Based Care
The IOCDF is proud to be a member of the Mental Health Liaison Group, which distributed the below statement. To learn more about appropriate treatment for OCD, including the use... Read more » The post Statement on Mental Health and…
Genotype-Guided Antidepressants Could Have Long-Term Benefits
Prescribing selective serotonin reuptake inhibitors according to a patient’s genetic makeup may have benefits, but these may only become apparent in the long term. The post Genotype-Guided Antidepressants Could Have Long-Term Benefits appeared first on Inside Precision Medicine.
Brief report: joint trajectories of anxiety and depression symptoms in an inception cohort of autistic youth
Background and AimsAnxiety and depression symptoms are common among autistic youth, yet little is known about the pattern and relationship of their trajectories from childhood into adolescence, a period of increasing social and academic demands.MethodsThis study used parallel process latent…
Impact of COVID-19 pandemic on autism spectrum disorder service providers in Qatar: challenges, insights, and lessons learned
PurposeThe COVID-19 pandemic disrupted essential services, posing unique challenges for individuals with Autism Spectrum Disorder (ASD) who depend on consistent, specialized support. Service providers faced unique challenges in adapting to remote delivery methods, highlighting the fragility of existing systems during…
Real-world use of brexpiprazole during inpatient treatment for schizophrenia: continuation, discontinuation, and concomitant psychotropics
IntroductionIn the treatment of schizophrenia, antipsychotics used during acute inpatient care must control acute symptoms while remaining sufficiently tolerable to support treatment beyond the acute phase. Brexpiprazole, a serotonin-dopamine activity modulator may be one such option; however, its real-world use…
The Role of a Brief Educational Video Series for Parent of Adolescents With Anorexia Nervosa
Conditions: Atypical Anorexia Nervosa; Anorexia Nervosa Interventions: Behavioral: Parent Educational Videos; Behavioral: Treatment as usual for adolescents with Anorexia Nervosa Sponsors: Baylor College of Medicine Enrolling by invitation
TUBSIS 2.0 – Tobacco Use Behavioral Support and Intervention System
Conditions: Tobacco Use Disorder; Nicotine Dependence; Vaping; Smoking Tobacco Interventions: Behavioral: TUBSIS 2.0 Sponsors: University of Zurich; State Secretariat for Education Research and Innovation, Switzerland Recruiting