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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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373 results
Drug Target for Fragile X Syndrome Identified Through Preclinical Study
Researchers identified the synaptic protein EPAC2 as a potential therapeutic target for fragile X syndrome, and showed that blocking EPAC2 in an FXS mouse model restored abnormal patterns of brain activity and improved several FXS-associated behavioral symptoms. The post Drug…
AI Model Predicts Alzheimer’s Progression from a Single MRI Scan
A new AI framework developed by UCSF researchers can predict Alzheimer’s disease progression and future cognitive decline from a single MRI scan without requiring PET imaging, fluid biomarkers, or baseline cognitive testing. The post AI Model Predicts Alzheimer’s Progression from…
Amelioration of tic disorder by Jujuboside A via gut microbiota remodeling and intestinal 5-HT signaling
BackgroundTic disorder (TD) is a common chronic neuropsychiatric condition manifesting during childhood and adolescence. Jujuboside A (JuA) may alleviate TD symptoms; however, the mechanisms underlying its therapeutic effects remain unclear.MethodsWe established a rat model of TD and used histological techniques…
Neurocognitive function among individuals with problematic social media use
BackgroundWith the development of technology and the internet, social networks gained momentum quickly and play a central role in daily activities. Despite this, there is a public health concern over excessive or problematic social media use. There is also a…
Heatwave-related variations in psychiatric consultations and admissions: a time-series analysis
BackgroundHeatwaves are becoming increasingly frequent and intense across Europe, posing significant risks to physical and mental health. Emerging evidence suggests that prolonged exposure to high temperatures may exacerbate psychiatric symptoms and increase the demand for acute mental health services.ObjectivesThis study…
Adding VR-Based Episodic Future Thinking Training to Executive- Function Training for Children With ADHD: A Randomized Controlled Trial
Conditions: ADHD Interventions: Behavioral: executive function; Behavioral: a VR-based episodic future thinking Sponsors: Qilu Hospital of Shandong University Completed
Comparative Outcomes of VR and In-person Interventions for Preschool-aged Children With Autism Spectrum Disorder
Conditions: Autism Spectrum Disorder High-Functioning; Autism Spectrum Disorder (ASD) Interventions: Behavioral: Virtual Reality-Based Social Skills Group Intervention; Behavioral: In-Person Social Skills Group Intervention Sponsors: National Cheng-Kung University Hospital Completed
Personalized Pharmaco-Lifestyle Interventions for Severe Mental Illnesses (LIFETRAIN)
Conditions: Severe Mental Illness; Depression / Major Depressive Disorder; Bipolar Disorder (BD); Schizophrenia Interventions: Drug: Semaglutide (SEMA); Behavioral: Exercise module; Behavioral: Anti-inflammatory diet module; Behavioral: Sleep intervention module; Behavioral: Social prescribing module; Device: Closed-loop transcranial alternating current stimulation (CL-tACS); Behavioral:…
Factors Influencing the Initiation and Continued Engagement of Digital Mental Health Tools Among Adults: Theory of Planned Behavior–Informed Systematic Review
Background: Digital mental health tools (DMHTs) offer scalable support, but engagement varies. Understanding the shapes of initiation and ongoing use is essential for effective design and implementation. Objective: This study aims to synthesize determinants of adults’ initiation and engagement with…
Reducing Intrusive Trauma Memories Using a Brief Mental Imagery Competing Task Intervention: Case Series of Trauma-Exposed Women in Iceland
Background: There is a need for scalable and simple interventions for trauma-exposed people. In this case series, we built on our previous case study and case series findings and further explored the use and potential effectiveness of a brief novel…
Large Language Models and Their Applications in Mental Health: Scoping Review
Background: Large language models (LLMs) are poised to transform mental health care, offering advanced capabilities in diagnosis, prognosis, and decision support. Since their inception, numerous mental health-focused LLMs have emerged in the scientific literature, reflecting the growing interest in leveraging…
A hierarchical machine learning model for predicting self-harm and suicidal behaviour in hospitalised patients with schizophrenia using clinical history and nursing observations
ObjectiveThis study aimed to develop and evaluate a two-layered machine learning framework that combines admission clinical information with longitudinal nursing observations to identify schizophrenia inpatients at high risk of self-harm or suicidal acts.MethodsWe retrospectively reviewed the records of 477 patients…
Context-dependent interaction between oxytocin gene polymorphisms and alcohol dependence in modulating negative emotions during acute alcohol withdrawal in adult males
ObjectiveThe importance of multiple gene-environment interaction (G × E) has been highlighted in understanding the etiology of negative emotions. This study examines the impact of oxytocin (OXT) polymorphisms (rs2740210, rs6133010, and rs2740209) in combination with alcohol dependence on anxiety and…
Validation of a criterion-based screening and triage pathway for adult ADHD: a prospective observational study of safety and operational efficiency
BackgroundThe increasing demand for adult attention-deficit hyperactivity disorder (ADHD) assessments has required the development of efficient triage pathways. This study provides a formal assessment of a criterion-based screening model designed to prioritise patient safety and operational efficiency within a National…
Protracted encephalopathy and subacute combined degeneration associated with chronic nitrous oxide use: a case report
Nitrous oxide is a dissociative hallucinogen that is increasingly used recreationally, in part due to its widespread availability. Its use is known to cause subacute combined degeneration via inactivation of vitamin B12; it may also result in acute delirium and…
Parsing autism spectrum heterogeneity through fMRI
Nature Neuroscience, Published online: 15 May 2026; doi:10.1038/s41593-026-02269-1Autism is remarkably heterogeneous, posing a long-standing challenge for linking genetics to brain dynamics. A cross-species study identifies two principal dysconnectivity signatures across 20 mouse models of autism risk, each associated with distinct…
Retail-Grade Weighted Blanket Effectiveness on ADHD-related Sleep Disturbances (BEAD)
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity Interventions: Device: Sleep Intervention with weighted device Sponsors: University Hospital Bispebjerg and Frederiksberg Not yet recruiting
Online Evaluation of the Diagnostic Accuracy of BlinkLab’s Digital Assessments for Autism
Conditions: Autism; Autism Spectrum Disorder; Autism Spectrum Disorder (ASD); Neurodevelopmental Conditions Interventions: Diagnostic Test: BlinkLab Dx1; Behavioral: Retrospective Neurodevelopmental Diagnostic Assessment Sponsors: Blinklab Limited Recruiting