Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Emotional maltreatment and problematic short-video use among adolescents: an indirect association through narcissism and moderation of the direct association by physical activity
IntroductionEmotional maltreatment has been associated with problematic short-video use during adolescence, but the nature of this association remains unclear. This cross-sectional study examined the association between emotional maltreatment and problematic short-video use, estimated the indirect statistical association through narcissism, and…
STAT+: The head of Kennedy’s new autism project served in Iraq War, worked with Sesame Street
Advanced Research Projects Agency for Health is planning a total-lifespan research project on autism: A Q&A with its leader, Russell Shilling.
Acceptability and Efficacy of a Culturally Adapted, Low-Frequency Parent-Mediated Early Start Denver Model (ESDM) Versus Standard Care in Young Children With Autism
Conditions: Autism Spectrum Disorder Interventions: Behavioral: Early Start Denver Model Sponsors: National University Hospital, Singapore Completed
AI Mental Health Tool vs. Psychoeducation Control
Conditions: Depressive Disorder; Depressive Symptoms Interventions: Behavioral: Ash; Behavioral: Brief Therapist-Delivered Telehealth Sponsors: Slingshot AI Active, not recruiting
A Persian AI-Based CBT Chatbot and Voice Analysis System for Managing Perceived Stress
Conditions: Psychological Stress; Perceived Stress Interventions: Behavioral: Persian AI-Based CBT Chatbot; Behavioral: Active Mental Health Content Sponsors: Hamid Reza Marateb; Isfahan University of Medical Sciences; University of Isfahan Not yet recruiting
Identifying Suicide Risk Based on the Words People Use
Researchers from the Child Mind Institute and MIT have developed a tool that can identify warning signs in text conversations, helping experts better understand who may need urgent support. The post Identifying Suicide Risk Based on the Words People Use…
Practical Guide to Large Language Models for Information Extraction in Behavioral Health Notes: Tutorial
Background: Mental health clinical notes contain decision-critical information often absent from structured electronic health record fields. Large language models (LLMs) can extract clinically relevant signals from narrative text; however, variability in output format, limited reproducibility, and inconsistent evaluation remain barriers…
Prevalence of positive screens for depression, anxiety, and PTSD symptoms among parents of infants admitted to a NICU: a pilot study
IntroductionParents of infants admitted to the Neonatal Intensive Care Unit (NICU) may experience substantial psychological distress. This study aimed to assess the prevalence of positive screens for depressive, anxiety, and post-traumatic stress disorder (PTSD) symptoms and to explore their associations…
Effects of psychedelic drug use on neurocognitive function and the psychological and social domains of quality of life: an international online study
BackgroundThe past few decades have seen a revived interest in psychedelic-assisted and ketamine-assisted therapy for mental health disorders, but data concerning the acute, subacute, and long-term effects of serotonergic psychedelics on cognitive functioning are scarce. This international, online study (N = 759)…
Effect of transcranial alternating current stimulation (NET Device™) on psychostimulant withdrawal severity and time course: a real-world data analysis
BackgroundPsychostimulant use disorder is a life-threatening condition with no FDA-approved treatment. Stimulant withdrawal symptoms impede treatment engagement and are unaddressed by standard of care. The NET Device, a non-invasive transcranial alternating current stimulator, is FDA-cleared for opioid withdrawal suppression. No…
Exploring the interplay of discrimination perception, alexithymia, and shyness among hearing-impaired college students: a network approach
BackgroundHearing-impaired college students face limitations in auditory and verbal communication, placing them at higher risk for mental health problems. While previous studies have mostly used traditional structural equation models to examine the relationship between discrimination perception and psychological adaptation issues,…
Case Report: Rapid resolution of psychogenic cough in an adolescent following bromazepam treatment
BackgroundSomatic cough syndrome, formerly termed psychogenic cough or habit cough, is an under-recognized cause of chronic cough in pediatric populations, characterized by repetitive, dry, and honking cough that is absent during sleep. Behavioral interventions are first-line treatment with high success…
Delayed-Release, Extended-Release Methylphenidate (Jornay PM) for Adolescents and Young Adults With ADHD and Cannabis Use Disorder
Conditions: ADHD; Cannabis Use Disorder Interventions: Drug: Delayed-release, extended-release methylphenidate; Drug: Placebo Sponsors: Massachusetts General Hospital; National Institute on Drug Abuse (NIDA); Collegium Pharmaceutical, Inc. Not yet recruiting
Enhancing Emotion Regulation in Children With Autism Through Extended Reality
Conditions: Autism; Emotion Regulation Difficulties Interventions: Behavioral: Extended Reality; Behavioral: Emotion regulation coaching Sponsors: Johannes Kepler University of Linz; Interdisciplinary Transformation University Austria; Hospital of St.John of God, Linz Completed
Implementing BEAM: A Scalable Digital Mental Health Program, for Families of Children Referred to Neurodevelopmental Services
Conditions: Depression and Anxiety Symptom; Anger; Parenting; Stress (Psychology); Parent Child Relationship; Child Development; Neurodevelopmental Conditions Interventions: Behavioral: The Building Emotional Awareness and Mental Health (BEAM) Program Sponsors: University of Manitoba; Children's Hospital Research Institute of Manitoba; Kids Brain Health…
Creative Art Teletherapy for Veterans With PTSD
Conditions: Post-Traumatic Stress Disorder F03.950.750.500 D013313 Interventions: Behavioral: Art-therapy Remote Treatment for Veterans Experiencing Trauma Sponsors: VA Office of Research and Development; Henry M. Jackson Foundation for the Advancement of Military Medicine; Drexel University Not yet recruiting
Standardized Manual-Based Smoking Cessation Treatment in Patients With Comorbid Mental Disorders: Qualitative Interview Study
Background: Smoking prevalence is disproportionately high among individuals with mental disorders, who also show reduced cessation success, suggesting that current cessation interventions may not fully address their specific needs. A barrier to smoking cessation is the fear that quitting may…
Trajectories of Persistent Exposure to Self-Harm–Encouraging Websites and Subsequent Mental Health Outcomes in US Youth: Longitudinal Cohort Study
Background: Self-harm, including suicidal thoughts, self-injurious behavior, and disordered eating, is a major public health concern among adolescents and young adults. Youth increasingly encounter self-harm–related content online, including websites that explicitly encourage harmful behaviors. Although exposure to such content has…
Relationship between loneliness and self-efficacy: the mediating role of internet addiction and the moderating role of sleep quality
IntroductionThis study aimed to examine the association between loneliness and self-efficacy among adolescents and to investigate whether internet addiction mediated this association and whether sleep quality moderated the direct and indirect pathways. Although previous research has demonstrated significant associations between…
Beyond dopamine: KarXT and emerging mechanism-based therapies in schizophrenia
KarXT (marketed as Cobenfy™), a fixed-dose combination of xanomeline and trospium chloride, represents the first new mechanism of action of an antipsychotic used for adult schizophrenia approved by the US Food and Drug Administration (FDA) in over 30 years. While…

