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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Early Detection of Alzheimer’s Disease and Related Dementias From Spontaneous Speech Using Foundation Speech and Language Models: Comparative Evaluation
Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is critical for timely intervention and care planning. However, current diagnostic methods are often inaccessible, costly, and delayed, especially for underserved populations. There is a growing…
Roles of NRXN1 in neuropsychiatric disorders: from genetic lesion to molecular mechanism
Numerous neuropsychiatric disorders frequently exhibit overlapping genetic risk factors, implying the molecular basis for their comorbidity. Nevertheless, the pathogenesis of these disorders remains elusive, particularly regarding how genetic variations impair the physiological function of risk genes and contribute to disease…
Direct modulation of human GABA-A α1β2γ2 receptors by the endocannabinoid 2-arachidonoylglycerol: implications for cannabinoid-related ligands and limitations for anxiolytic drug development
Anxiety disorders are associated with impaired inhibitory neurotransmission mediated by γ-aminobutyric acid type A (GABA-A) receptors. Although benzodiazepines remain effective anxiolytics, their clinical utility is limited by sedation, cognitive impairment, tolerance, and dependence, prompting the search for mechanistically distinct GABAergic…
Romanian male patients with the dual diagnosis of schizophrenia and alcohol use disorder: a prospective study of clinical, social, and treatment-related factors affecting quality of life
BackgroundSchizophrenia frequently co-occurs with alcohol use disorder (AUD), resulting in a complex clinical profile associated with poor functional outcomes and reduced quality of life (QoL). Although both conditions independently impair psychosocial functioning, few studies have examined the combined effects of…
Assessing directional connections between symptoms, cognition, insight, and real-life functioning in schizophrenia: a partial ancestor graphs analysis
IntroductionSchizophrenia is a severe chronic mental disorder causing significant global disability. Understanding the intricate relationships between symptoms, cognitive functions, and real-life outcomes is essential for developing effective interventions. Prior research, while informative, could not often determine the direction of the…
Internalizing and externalizing pathways to internet gaming disorder: the roles of anger and social anxiety
BackgroundInternet Gaming Disorder (IGD) represents a significant behavioral health concern, yet the roles of internalizing and externalizing psychological vulnerabilities in its development remain underexplored, particularly in Arabic-speaking populations.ObjectiveThis study examined anger and social anxiety as distinct externalizing and internalizing predictors…
From cats to cortex: T. gondii and psychosis, depression, and anxiety
This review examines whether cat ownership, via exposure to the neurotropic parasite T. gondii, contributes to vulnerability for psychotic, depressive, and anxiety symptoms. T. gondii establishes lifelong latent infection in the brain and muscle, where it can modulate dopaminergic signaling,…
The Download: a Nobel winner on AI, and the case for fixing everything
This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Three things in AI to watch, according to a Nobel-winning economist A few months before he…
Revolution’s aftermath: population based cross-sectional study to understand the intergeneration mental health and wellbeing following the 2024 student-led uprising
BackgroundBangladesh was confronted with a nationwide student uprising in July 2024, that exposed both participants and observers to widespread unrest and traumatic events. To better understand the kind of support the population will need, it is important to understand its…
Therapeutic Interventions Targeted at Problematic Use of Digital Technology: Systematic Review and Meta-Analysis of Evidence
Background: Problematic use of digital technology has increased across the world. Despite growing research, evidence on treatment effectiveness across digital behaviors remains fragmented. Objective: This study aimed to systematically evaluate and compare the effectiveness of therapeutic interventions targeted at problematic…
The Child Mind Institute Hosts 2026 Spring Luncheon “Future-Proofing Your Kids: Empowered Parenting in the Digital Age”
The event brought together advocates and distinguished individuals dedicated to equipping children and families with the skills they need to thrive in today’s rapidly evolving online and social environments. The post The Child Mind Institute Hosts 2026 Spring Luncheon “Future-Proofing…
Brain Histamine Map Links Genetic Factors to Mental Health and Psychiatric Disorders
Researchers mapped the histamine system in the brain, providing a new framework for understanding how this chemical system contributes to brain function, and potentially pointing towards new treatment strategies for histamine-related conditions such as depression, ADHD, and schizophrenia. The post…
Alexa Grasso on Mental Health Fitness
Alexa Grasso knows the importance of prioritizing her mental well-being alongside her physical training. The post Alexa Grasso on Mental Health Fitness appeared first on Child Mind Institute.
Applications Open for the SNF Global Center Communicator Fellowship
The fellowship is designed to support a new generation of communicators working to shape child and adolescent mental health care in low- and middle-income countries, in addition to the SNF Global Center’s core country offices in Brazil, Greece, and South…
The dual-burden of professional and academic stress: a cross-sectional mapping of mental health status and coping efficacy among postgraduate students in Nairobi, Kenya
BackgroundPostgraduate students face a dual burden of intense academic rigour and professional responsibilities, a dynamic particularly pronounced in growing economic hubs such as Nairobi, Kenya. While global literature highlights rising psychological distress in higher education, there is limited evidence on…
RESCUE- expected usefulness and willingness to participate in a trauma-informed group intervention for coping with traumatic work experiences in the emergency medical services
Emergency Medical Services personnel (EMS) are confronted with potentially highly stressful and traumatic occupational experiences, placing them at high-risk for mental disorders. Avoidant coping mechanisms, internalized and occupational stigma not only impede disclosure of and processing the incident-related stress but…
Integrating dual-process decision making and social dynamics: A formal modeling framework for addiction.
Currently, formal models of addiction focus either on the complex individual decision-making processes involved in addiction or on the social dynamics of addiction. They do not integrate these two levels, which has been identified as a key shortcoming of current…
Explore the Impacts of Theta Burst Stimulation Over the Right Inferior Frontal Gyrus in Autism Spectrum Disorder: Combination of Clinical Symptoms, Neuropsychological Function and MRI
Conditions: Autism Spectrum Disorder; Theta Burst Stimulation; Right Inferior Frontal Gyrus Interventions: Device: intermittent theta burst stimulation Sponsors: Chang Gung Memorial Hospital Recruiting
Understanding and Targeting Self-Regulatory Control in Bulimia Nervosa
Conditions: Bulimia Nervosa; Feeding and Eating Disorders; Mental Disorders Interventions: Other: Real fNIRS Neurofeedback; Other: Sham-Control fNIRS Neurofeedback; Other: SmartPhone Intervention Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting
Incorporating Narrative Into the Treatment of Youth With Anorexia Nervosa (Virtual)
Conditions: Anorexia Nervosa Interventions: Behavioral: Narrative Medicine (NM) Workshop Series Sponsors: University of California, San Francisco Recruiting