Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Maternal folate receptor alpha autoantibodies and folate levels during pregnancy in relation to autism spectrum disorder: a pilot case-control study
BackgroundFolate receptor alpha autoantibodies (FRAA) are reported to be associated with autism spectrum disorder (ASD) and are found more frequently in mothers of children with ASD. However, the relationship between maternal FRAA during pregnancy, folate status, and ASD risk in…
Low-burden speech-based screening of depressive symptoms using ultra-short speech samples
BackgroundSpeech holds promise for depressive symptom screening, but practical applications require clearer guidance on effective segmentation, optimal speech tasks, minimum duration, and feature-model matching.ObjectiveTo enable low-burden screening for depressive symptoms, this study aims to evaluate the effectiveness of short speech…
Opinion: Mentally ill women deserve more support to have children
“The maternal mental health needs of women like me have been badly underprioritized in American society,” writes Meg LeDuc.
Predicting the Outcome of ADHD in White Matter Injure Neonates With Multi-modality MRI
Conditions: White Matter Abnormalities, Nonspecific; ADHD; Neurodevelopment Outcome Sponsors: First Affiliated Hospital Xi'an Jiaotong University Completed
Novel Approaches to Supporting Students With ADHD in Multi-Tiered Systems of Support
Conditions: Attention Deficit Hyerpactivity Disorder Interventions: Behavioral: Academic Competency Enhancement (ACE) classroom; Behavioral: School as Usual Classroom Supports Sponsors: Florida International University Not yet recruiting
Irreconcilable differences?: epistemic injustice and the integration of mental healthcare for LGBTQ+ young people
BackgroundIntegrated youth mental healthcare is an approach that has evolved in response to the global escalation of young people’s poor mental health, and the failure of current mental health systems and models to improve this situation. Lesbian, gay, bisexual, transgender,…
In Vivo Characterization of Fatty Acid Amide Hydrolase in Posttraumatic Stress Disorder: A [11C]CURB Positron Emission Tomography Study
Posttraumatic stress disorder (PTSD) is associated with impaired fear extinction and dysfunction in amygdala-centered circuits, for which treatments remain insufficient. The endocannabinoid system, particularly anandamide signaling regulated by fatty acid amide hydrolase (FAAH), has been implicated in stress and fear…
Effectiveness and Usability of Digital Slow Breathing and Detached Mindfulness Interventions in Late Adolescents: Mixed Methods Study
Background: Many adolescents experience elevated stress and anxiety; yet, access to effective psychological support is limited. Brief digital mental health interventions, such as slow breathing (SB) and detached mindfulness (DM), offer a potentially scalable approach to promoting emotion regulation in…
Bone Density Linked with Brain Function
Lower bone density is linked with worse cognitive function, which may help identify postmenopausal women at risk of parallel skeletal and neurologic decline. The post Bone Density Linked with Brain Function appeared first on Inside Precision Medicine.
The Importance of Intergenerational Dialogue
How the Stavros Niarchos Foundation (SNF) Global Center’s second annual Global Summit on Youth Mental Health is advancing opportunities for young people and experts to exchange perspectives and shape priorities together. The post The Importance of Intergenerational Dialogue appeared first…
Pilot evaluation of an educational and lived experience training program on ketogenic metabolic therapy in mental health care for health care professionals
BackgroundSerious mental illness imposes a substantial burden. Pharmacologic treatments remain only partially effective and are associated with significant side effects, highlighting the need for novel treatment approaches. Ketogenic metabolic therapy (KMT) is emerging as an intervention for serious mental illness,…
Neural mechanisms of uncertain decision-making in anxious adolescents: an EEG study based on the balloon analogue risk task
BackgroundAdolescence is marked by heightened vulnerability to anxiety which can impair decision-making under uncertainty. The underlying neural oscillatory network-level mechanisms in anxious adolescents require further elucidation.MethodsWe recruited 40 adolescents (20 adolescents with clinically diagnosed anxiety disorders, 20 matched controls). Participants…
Methamphetamine-withdrawal catatonia resolved with mixed amphetamine salts: a case report
Catatonia is a well-recognized psychiatric emergency with an evolving understanding of its underlying pathophysiology. However, withdrawal-associated catatonia remains poorly characterized. Here we describe a 32-year-old man with symptoms consistent with methamphetamine-withdrawal catatonia, a previously undescribed etiology, which resolved only after…
New federal autism committee head has financial ties to leucovorin
RFK Jr. has installed John Gaitanis, a pediatric neurologist, as the new chair of the Interagency Autism Coordinating Committee, which helps the federal government decide how to allocate roughly $2 billion…
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Conditions: ADHD Interventions: Behavioral: Group CBT based on DBT-skills training; Behavioral: Activity group Sponsors: Region Stockholm Recruiting
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
Conditions: Borderline Personality Disorder; Borderline Personality Pathology; Depressive Symptoms; Emotion Dysregulation; Suicidal Ideation Interventions: Drug: Psilocybin; Behavioral: Psilocybin-Assisted Therapy With Dialectical Behavior Therapy Sponsors: University of Minnesota; Filament Health Corp. Not yet recruiting
Agreement Between a Mobile Self-Administered Comprehensive Geriatric Assessment Screening Tool and Geriatrician-Administered Assessment: Cross-Sectional Feasibility Study
Background: Comprehensive geriatric assessment (CGA) is a widely recommended, multidimensional approach for guiding clinical decision-making and management in older adults. However, its implementation remains limited by a shortage of geriatric specialists, the complexity of geriatric care, and the increasing demands…
Supporting the Primary Outcomes of the Mirai Trial for the Adjunctive Digital Therapeutic Rejoyn (CT-152) in the Treatment of Major Depressive Disorder: Meaningful Change Analysis in the Montgomery-Åsberg Depression Rating Scale
Background: Rejoyn (CT-152) is a prescription digital therapeutic (DTx) adjunct to antidepressive medication authorized for patients with major depressive disorder. To better understand the patient benefit of DTx and other treatment modalities, current regulatory standards support the use of modern…
STAT+: Pharmalittle: We’re reading about Novo plans to expand its pipeline, early Alkermes ADHD data, and more
Novo Nodisk outlined plans to expand its pipeline and find new products that it could sell more like consumer goods than traditional medicines