Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Orexin receptor antagonists for sleep disturbance in attention-deficit/hyperactivity disorder and autism spectrum disorder: a systematic review
BackgroundSleep disturbance is among the commonest and most impairing comorbidities of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Melatonin has the strongest evidence base, but its action is chronobiotic, its maintenance effect inconsistent, and adult evidence sparse. Orexin receptor…
Temporal and demographic trends in deaths with co-recorded depressive disorders and digestive system diseases among U.S. adults: a 26-year nationwide analysis (1999–2024)
BackgroundDepression and digestive diseases are common public health concerns and may coexist through shared clinical and behavioral pathways. However, national mortality trends involving both conditions remain insufficiently characterized. This study examined temporal and demographic trends in deaths with co-recorded depressive…
Supporting Families of School-Aged Children With ADHD: A Dual-Generation Therapy Approach Through the BRIDGE Program
Conditions: ADHD; Maternal Mental Health; Dialectical Behavior Therapy; Parenting Intervention; Children Interventions: Behavioral: BRIDGE-ADHD Sponsors: University of Manitoba Not yet recruiting
A Study of Remission Criteria in Anorexia Nervosa: A Multidimensional Exploratory Observational Study of Recovery Among Patients in Remission According to the Bardone-Cone Criteria
Conditions: Anorexia Nervosa Interventions: Other: Scales and questionnaires Sponsors: Federation Regionale de Recherche en Psychiatrie et Sante Mentale Occitanie Not yet recruiting
Furthering the Understanding of Psilocybin Use and Molecules Relevant to Depression and Schizophrenia
American Journal of Psychiatry, Volume 183, Issue 11, Page 807-810, November 01, 2026.
Toward Proteomic Biomarkers of Atypical Depression
American Journal of Psychiatry, Volume 183, Issue 11, Page 811-813, November 01, 2026.
PTSD is Associated with Advanced Epigenetic Age in 43,155 US Military Veterans
Posttraumatic stress disorder (PTSD) has been associated with advanced biological age in DNA methylation data, but results have been inconsistent. This study evaluated PTSD in association with epigenetic age in the largest cohort to date (by ∼20 fold).
Transcranial pulse stimulation in the treatment of cognitive disorders of aging: a systematic review
IntroductionNon-invasive brain stimulation techniques, specifically transcranial pulse stimulation (TPS) are of increasing interest due to their potential to fill in gaps left by current pharmacological treatments in cognitive disorders of aging. The current review’s aims were to systematically determine what…
Dance-based exercise for healthy brain aging in older adults: integrating neuroplasticity, cognitive reserve, physical fitness, social engagement, and mental well-being
Population aging brings rising difficulties associated with cognitive deterioration, diminished physical capabilities, social isolation, and increased susceptibility to mental health problems. Finding accessible, multidomain approaches to promote healthy brain aging has become a major priority. Dance-based exercise is a distinctive…
Risk and protective factors for suicidality in older adults: an umbrella review and framework for multidimensional suicide risk assessment
IntroductionSuicidality in older adults is a major public health concern influenced by psychiatric, psychological, physical, functional, social, and socioeconomic factors. However, the evidence remains fragmented, and protective factors have received substantially less attention than risk factors.MethodsThis umbrella review followed JBI…
10 Hz repetitive transcranial magnetic stimulation for nitrous oxide dependence: a case report
Nitrous oxide (N2O) abuse has emerged as an increasingly serious public health concern, yet effective interventions for N2O dependence remain lacking. We report on a 21-year-old woman with N2O dependence who, after 6 months of repeated N2O inhalation, developed gait…
A gait foundation model for prediction of multisystem health phenotypes from 3D skeletal motion
Nature Medicine, Published online: 06 November 2026; doi:10.1038/s41591-026-04724-9A gait foundation model, developed using three-dimensional skeletal motion data from 3,328 adults, predicts a wide array of clinical characteristics and diagnoses, including cardiometabolic, mental health and frailty phenotypes.
AI-assisted Home-based Intervention for ADHD Children
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity; ADHD - Combined Type; ADHD - Inattentive Type Interventions: Device: Generative artificial intelligence assisted diary platform home-based intervention; Behavioral: Consultations and psychoeducation on child emotional management Sponsors: National Taiwan University Hospital Recruiting
Preventive and Personalized Digital Emotion Regulation Skills Intervention to Reduce Depression and Anxiety in Youths With Adverse Childhood Experiences
Conditions: Adverse Childhood Experience; Depression / Major Depressive Disorder; Anxiety Depression; Anxiety Interventions: Behavioral: Lifestyle psychoeducation intervention; Behavioral: Personalized digital psychoeducation intervention on emotion regulation Sponsors: Institute of Mental Health, Singapore Not yet recruiting
Modeling of Therapist-Client Dynamics in Psychotherapy Using Large Language Model–Based Assessments: Retrospective Observational Study of 1573 Psychotherapy Sessions
Background: Psychotherapy is a primary treatment for many mental health conditions, yet the dynamic interplay among therapist behaviors, client responses, and the therapeutic relationship remains difficult to disentangle at scale. Traditional process research relies on labor-intensive human coding, limiting the…
An Unfortunate Loop: How the OCD Care Crisis Delays Research
By Boris Litvin, MA In December 2025, the IOCDF released its first white paper America’s OCD Care Crisis: National Findings on the Failure of Effective OCD Treatment to Reach Patients.... Read more » The post An Unfortunate Loop: How the…
Adolescent depression in Chinese schools and families: a case study of 20 adolescents
This study examines adolescent depression within Chinese families and educational environments through an action research approach, engaging researchers and practitioners in continuous cycles of observation, intervention, and reflection. Within this iterative process, direct counselling sessions and family therapy were deployed…
The nonlinear relationship between symptoms of internet addiction and depressive symptoms: an empirical study among Chinese university students
ObjectTo examine the nonlinear dose-response association between IA and depressive symptoms, while also exploring potential variations in this association across demographic subgroups.MethodsA cross-sectional study was administered to Chinese university students. Internet addiction (IA) was assessed using an 8-item standardized diagnostic…
“Like a never-ending performance of myself”: trans autistic experiences of identity, camouflaging and the complex closet
IntroductionBoth camouflaging and closeting one self conceal identity traits that are deemed undesirable or reprehensible by society at large. They serve as a mean of survival in a world that discriminates against autistic and trans people, but frequently lead to…
Understanding the role of dysfunctional hippocampal-parahippocampal representations of space in schizophrenia
The etiology of schizophrenia is yet to be fully understood, thus limiting the scope of interventions for symptom reduction. Among features less frequently researched and addressed are deficits in spatial cognition, which may contribute to cognitive disorganization, a core symptom…

