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AI-Assisted Analysis of Spontaneous Affective Facial Responses for Cognitive Status Assessment in Older Adults: Exploratory Feasibility Study

Background: As Taiwan enters a super-aged society, the prevalence of dementia continues to rise, highlighting the need for scalable, noninvasive approaches to identify behavioral alterations associated with cognitive decline. AI-based analysis of spontaneous affective facial responses has emerged as a…

Tags: Academic research, Mental health

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Experiences of suicidal behaviour and perceived triggers among young people and caregivers at a tertiary healthcare facility in Kenya

BackgroundSuicidal behavior among adolescents and young adults remains a major public health concern. In sub-Saharan Africa, however, qualitative work that captures both youth and caregiver perspectives is still limited. This study explored the experiences of suicidal behavior, perceived triggers and…

Tags: Academic research, Depression, Healthcare provider, Mental health, Mood and emotional regulation

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Encoded Therapeutics Reports Promising Results for Dravet Gene Therapy

Encoded Therapeutics reports promising early Phase I/II results for its AAV gene therapy developed to treat children with Dravet syndrome, a rare neurodevelopmental disorder characterized by severe epilepsy. The post Encoded Therapeutics Reports Promising Results for Dravet Gene Therapy appeared…

Tags: Clinical trial, Medication, Mental health, United States

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Case Report: A novel hemizygous nonsense variant in PPP1R3F gene associated with developmental delay, intellectual disability and autism spectrum disorder

BackgroundPPP1R3F deficiency syndrome is an extremely rare, recently identified X-linked recessive neurodevelopmental disorder. It is caused by hemizygous variants in the PPP1R3F gene, which encodes a glycogen-targeting subunit of the brain-specific protein phosphatase 1 (PP1). Dysfunction of PPP1R3F disrupts glycogen…

Tags: Academic research, Autism, Genomics, Mental health

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Research progress on developmental characteristics and clinical intervention of restricted and repetitive interests/behaviors in autism spectrum disorder across the lifespan: a narrative review

Restricted and repetitive interests/behaviors (RRBs) are a core symptom domain of autism spectrum disorder (ASD), with a significant impact on social interaction, learning, and overall functioning of autistic individuals. Clinical features of RRBs in ASD encompass repetitive sensorimotor (RSM) behaviors…

Tags: Academic research, Autism, Medication

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The association between depressive symptoms, physical activity, flow state, and resting-state EEG in college students

ObjectiveExploring the correlations among physical activity, flow state, and resting-state EEG in college students with depressive symptoms.MethodsA cross-sectional study was conducted among 216 college students. Participants completed questionnaires assessing depressive symptoms, physical exercise, and flow proneness, followed by a 5-min…

Tags: Academic research, Depression

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Daily digital gaming, weekly training duration, and perceived fatigue in athletes: indirect statistical associations involving digital game addiction awareness

IntroductionDigital gaming is a common leisure activity among athletes, yet its associations with weekly training duration and perceived fatigue remain insufficiently understood. This study examined the direct and indirect associations among daily digital gaming duration, weekly training duration, digital game…

Tags: Academic research, Substance abuse, Substance use

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Eating disorders are on the rise. GLP-1s could make things worse.

GLP-1 weight-loss drugs are one of the biggest biotech breakthroughs of the last decade. But to some clinical psychologists, they can represent something more sinister—a potential trigger for eating disorders. A new report suggests that the global incidence of anorexia…

Tags: Academic research, Appetite and ingestive regulation, Australia, Biotech, Eating patterns, Mental health

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What Are Night Terrors?

Growing up, my little brother experienced a phenomenon known as night terrors, though my parents, at first, weren’t sure what to call them. Extreme nightmares? Sleeping meltdowns? A born ’fraidy-cat, I would have guessed he had been possessed by a…

Tags: Academic research, Anxiety, Autism, Sleep and arousal regulation, Sleep-related parasomnias

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