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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Psychologists’ knowledge, attitudes, and training experiences regarding mental illness in individuals with intellectual disabilities in Saudi Arabia: a cross-sectional study
IntroductionIntellectual disability (ID) impacts an estimated 1-3% of the population worldwide, with a higher incidence in regions with limited healthcare access. In Saudi Arabia, current prevalence data, especially for adults, are scarce. This cross-sectional study explores the systemic challenges psychologists…
Clinical factors predicting tic persistence into adulthood
BackgroundDespite widespread patient and family interest in long-term outcome prediction at the time of Tourette syndrome (TS) diagnosis, there is limited data on factors associated with disease severity and impairment in adulthood. This study aimed to examine the relationship between…
Sleep and Drug Use: Neuroimaging Evidence for a Multidimensional Brain Framework
Sleep plays a critical role in the initiation and maintenance of drug use, as well as recovery among individuals with substance use disorders. Sleep is a multidimensional construct, and a growing body of research has demonstrated the relative independence of…
Circuit-Guided Neuromodulation for Anorexia Nervosa
Conditions: Anorexia Nervosa Interventions: Device: Intermittent theta-burst stimulation (iTBS); Device: Continuous theta-burst stimulation (cTBS); Device: Sham theta-burst stimulation Sponsors: Fundacao Champalimaud Not yet recruiting
Neurofeedback Therapy Added to Cognitive Behavioural Therapy-Based Psychoeducation for Test Anxiety Among Undergraduate Students: A Randomised Controlled Trial
Conditions: Test Anxiety; Test Anxiety Scale; Exam Anxiety Interventions: Device: Neurofeedback Therapy; Behavioral: Cognitive Behavioural Therapy-based Psychoeducation Sponsors: International Islamic University Malaysia Completed
Effectiveness of Interactive Techniques on Oral Hygiene Skills in a Group of Autistic Egyptian Children
Conditions: Autism Disorder; Autism Spectrum Disorder (ASD; Autism; Plaque Reduction; Plaque Induced Gingival Disease; Plaque Accumulation; Gingival Bleeding; Gingival Inflammation and Bleeding Interventions: Procedure: Peer model; Procedure: Pre-recorded video of peer modeling; Other: Pedagogical method Sponsors: Faculty of Dental Medicine…
Anti-Inflammatory Drug Target for Alzheimer’s, TBI, and Neurodegenerative Disease Identified
A study in human monocyte-derived microglia and human brain tissue slices suggests that inflammatory brain conditions, including traumatic brain injury and neurodegenerative diseases such as Alzheimer's disease, could be treated using an existing drug candidate targeting P2X7R. The post Anti-Inflammatory…
Depression and musculoskeletal diseases: a framework of systemic mechanisms
Musculoskeletal disorders (MSDs) encompass a broad spectrum of conditions affecting bones, joints, and muscles, characterized by significant pain and functional impairment, and have become a major global health burden. In recent years, accumulating evidence has revealed complex bidirectional interactions between…
EEG signature in psychiatrist’s subjective experience: a pilot study
IntroductionThe Assessment of Clinician’s Subjective Experience (ACSE) is a self-report questionnaire developed to evaluate clinicians’ subjective experiences during patient interactions. While its psychometric properties and clinical validity have been supported, its neurobiological correlates have not yet been investigated.MethodsIn this pilot…
Reduced contagious yawning in psychiatric disorders: a systematic review of potential social-cognitive mechanisms
IntroductionContagious yawning has been proposed to reflect multiple aspects of social cognition, including empathy, emotional contagion, self-processing, Theory of Mind (ToM), and action observation mechanisms such as the human mirror neuron system (hMNS). However, its underlying mechanisms remain debated, with…
Development and Evaluation of a Parent-led Intervention Module for Early Autism Spectrum Disorder (PRIME-ASD) in Odisha, India: Protocol for a Multiphase Mixed-methods Study Including an Open-label Randomised Controlled Trial
Conditions: Autism Spectrum Disorder Interventions: Behavioral: Behavioral: PRIME-ASD (Parent-led Intervention Module for Early Autism Spectrum Disorder); Behavioral: Behavioral: PRIME-ASD; Other: Treatment as usual Sponsors: All India Institute of Medical Sciences, Bhubaneswar Not yet recruiting
Cognitive and Behavioral Approaches to Reduce Binge Eating and Excess Weight in Adolescents (Online)
Conditions: Binge Eating; Overweight and Obesity; Eating Disorders in Adolescence Interventions: Behavioral: Cognitive-Behavioral Therapy for Adolescent Binge Eating; Behavioral: Lifestyle Behavioral Obesity Intervention; Other: Active Control Sponsors: Indiana University; National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) Not…
Brief Psychoanalytic Therapy Versus Cognitive Behavioral Therapy for Major Depressive Disorder
Conditions: Major Depressive Disorder (MDD Interventions: Behavioral: Brief Psychoanalytic Therapy; Behavioral: Cognitive Behavioral Therapy Sponsors: Istanbul Nisantasi University; Halic University; Uskudar University Not yet recruiting
Bilateral Theta-Burst Stimulation of Dorsolateral Prefrontal Cortex Regions for Late-Life Depression: A Randomized, Sham-Controlled Clinical Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 797-805, October 01, 2026.
Individualized Connectivity-Guided Versus Conventional Targeting of Accelerated Theta-Burst Stimulation in Depression: A Randomized, Double-Blind, Parallel-Design Trial
American Journal of Psychiatry, Volume 183, Issue 10, Page 775-784, October 01, 2026.
TMS-Evoked Cortical Reactivity Signatures as a Multidimensional Biomarker of Depression: A TMS-EEG Meta-Analysis from Diagnosis to Prognosis
Transcranial magnetic stimulation combined with electroencephalography (TMS-EEG) enables perturbation-based assessment of cortical reactivity and has emerged as a promising tool for identifying neurophysiological biomarkers in major depressive disorder (MDD). However, the literature remains fragmented, and TMS-EEG metrics have yet to…
Inhibitory control and error processing in Obsessive-Compulsive Disorder: A mega-analysis of task-based fMRI data by the ENIGMA-OCD consortium
Obsessive-compulsive disorder (OCD) is a chronic condition in which impaired inhibitory control and excessive error monitoring may contribute to maintenance of obsessions and compulsions. This mega-analysis investigates neural activation during response inhibition and error processing using adult (OCD=563; control=348) and…
Electronic Health Record–Based Phenotyping for Obsessive-Compulsive Disorder: Algorithm Development and Multicenter Validation Study
Background: Obsessive-compulsive disorder (OCD) is a common psychiatric disorder, with two-thirds of affected individuals reporting severe impairment. Despite its substantial burden and moderate heritability, the etiology of OCD remains poorly understood, and treatments are often suboptimal. Although recent genome-wide association…
Neurons Involved in Generating Anxiety After Cannabinoid Drug Exposure Identified in Mice
Working with mice, scientists have for the first time identified a set of neurons in the brain that play a role in generating anxiety after exposure to cannabinoid drugs, especially under stressful conditions. The post Neurons Involved in Generating Anxiety…