Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Canadian Hearing Services, in Partnership with the Mental Health Commission of Canada, Launches Canada’s First Mental Health First Aid Program Designed for Deaf Communities
TORONTO, ON — October 5, 2026 – Canadian Hearing Services, in partnership with the Mental Health Commission of Canada (MHCC), through Opening Minds, an initiative of MHCC, has launched Mental Health First Aid for the Deaf Community. Through this collaboration,…
Elderly abuse and anxiety symptoms among older adults in China: the mechanism of physical frailty and social frailty
PurposeThis study aims to examine the association between elderly abuse and anxiety symptoms among older adults and explore the mechanisms of physical frailty and social frailty between them.MethodsA total of 1361 older adults were included in this study. Multiple linear…
Usability of digital medicine systems in patients with schizophrenia or schizoaffective disorder
ObjectiveTo assess the usability and performance of digital medication management systems (DMS) for patients with stable ambulatory schizophrenia and schizoaffective disorder.MethodsThis prospective, interventional study comprised a screening phase (up to 4 weeks), training phase (3 weeks: system use under the…
Plant essential oils as a novel therapeutic strategy for depression and anxiety: emerging evidence and mechanisms
Depression and anxiety are major global mental health disorders that require safer and more accessible adjunctive interventions. This review uniquely integrates current evidence on plant essential oils in aromatherapy and identifies the cAMP–PKA–CREB pathway as a key mechanistic hub linking…
Increased frequency of rare damaging variants in PLIN4 in patients with anorexia nervosa
BackgroundAnorexia nervosa (AN) is a severe psychiatric disorder characterized by pathological fear of weight gain, persistent restriction of energy intake, and pervasive body image disturbance. Although AN is substantially heritable, the rare coding variants contributing to susceptibility remain incompletely defined.…
Group Skills Training (DBT vs CBT) for Alexithymia in Young Adult Women
Conditions: Alexithymia; Anxiety; Interpersonal Problems; Emotion Regulation Interventions: Behavioral: DBT-based Group Skills Training (DBT-GST); Behavioral: CBT-based Group Skills Training (CBT-GST) Sponsors: Atlas University; Istanbul Medeniyet University Completed
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
Conditions: Sleep Disturbance; Sleep Problems; Substance Use (Drugs, Alcohol); Anxiety; Depression Interventions: Behavioral: Transdiagnostic Intervention for Sleep and Circadian Dysfunction; Behavioral: Healthy habits psychoeducation Sponsors: Universidad Pública de Navarra Not yet recruiting
Child Mind Institute Study Finds Strong Link Between Teen Belonging and Mental Health
Released in recognition of World Mental Health Day on October 10, Building Bridges: Teen Loneliness and Connection asked 1,000 U.S. teens aged 14-17 what connection means to them, where they feel most connected, and who they turn to when they…
Nicotine and tobacco smoke reshape neuronal signaling networks from a single-nucleus transcriptomic perspective
Nicotine and cigarette smoke exposure significantly impact brain function, yet their distinct cellular and molecular mechanisms remain unclear. To address this, we conducted comprehensive single-nucleus RNA sequencing (snRNA-seq) analysis on whole-brain samples and specifically on the ventral tegmental area (VTA)…
Integrated transcriptomic and proteomic profiling reveals C3-associated hippocampal neuroimmune remodeling in sodium bicarbonate-treated sepsis-associated encephalopathy
BackgroundSepsis-associated encephalopathy (SAE) is a neurological complication of sepsis characterized by cognitive impairment and persistent brain dysfunction. Although neuroinflammation and glial activation contribute to SAE pathogenesis, the molecular alterations underlying hippocampal neuroimmune dysfunction remain incompletely understood. The potential role of…
Comparative efficacy of naltrexone-accelerated versus sublingual buprenorphine in opioid withdrawal management and initiating injectable naltrexone treatment: study protocol for a randomized controlled trial
BackgroundExtended-release injectable naltrexone (XR-NTX), a long-acting opioid antagonist, is an effective relapse prevention strategy in the treatment of opioid use disorder (OUD). However, standard XR-NTX initiation requires completion of opioid withdrawal management and a 1–2 week opioid-free period. This interval…
The dynamic features of long-term habituation of negative emotions: evidence from eye-tracking and hypothalamic-pituitary-adrenal axis research
ObjectivesNegative emotional habituation (NEH) plays a crucial role in individuals’ survival and adaptation. However, systematic research on long-term negative emotional habituation remains limited. This study aimed to explore the dynamics of the habituation process during prolonged repeated exposure to negative…
Sex differences in sleep architecture among patients with severe mental disorders: a polysomnographic study
BackgroundSleep disturbances are common in severe mental illness, including schizophrenia, bipolar disorder, and major depressive disorder. Yet sex-specific sleep patterns across schizophrenia, bipolar disorder, and major depressive disorder remain poorly characterized.MethodsIn this cross-sectional study, we compared overnight polysomnography between 372…
A comparison of recovery benefits associated with participation in SMART Recovery, AA, both SMART and AA, or neither, following a new alcohol use disorder recovery attempt
BackgroundSelf-Management and Recovery Training (SMART Recovery or “SMART”) is an internationally known “second-wave” addiction recovery mutual-help organization that has grown over several decades. Despite this, little is known empirically about who uses SMART and how they fare on important alcohol-specific…
Compulsive sexual behavior disorder and paraphilic disorders in a large Brazilian community sample: an online investigation
BackgroundThe International Classification of Diseases 11th Revision (ICD-11) includes Compulsive Sexual Behavior Disorder (CSBD) among impulse control disorders, aiming to standardize diagnostic criteria and improve the understanding of problematic sexual behaviors across cultures. However, few large-scale studies have investigated CSBD…
Mindfulness-Based Intervention for Parents of Autistic Children in Pakistan
Conditions: Autism Spectrum Disorder; Parental Stress Interventions: Behavioral: Stronger Together Mindfulness-Based Intervention; Behavioral: Psychoeducation Program Sponsors: Northeast Normal University Completed
Reliability of Childhood Autism Rating Scale, Second Edition, Assessments Using Telepsychiatry for Children With Neurodevelopmental Disorders and Their Caregivers: Randomized Feasibility Study
Background: The COVID-19 pandemic has increased the demand for telepsychiatry in neurodevelopmental assessment; however, few studies have examined the interrater reliability of clinician-rated autism scales, such as the Childhood Autism Rating Scale, Second Edition (CARS2), when used remotely. Although the…
Australian Digital Mental Health Services for Anxiety and Depression: Meta-Analysis and Comparison Study
Background: Mental Health Online, MindSpot, and THIS WAY UP are 3 Australian Government–funded digital mental health services (DMHSs). These services are free for consumers and deliver a range of (depression and anxiety disorder) psychological assessments and interventions using the internet,…
Effectiveness of Chatbots in Mental Health Screening and Assessment: Systematic Review
Background: Mental health disorders affect 970 million people globally; yet, over 50% do not access timely evaluation due to structural barriers and professional shortages. Chatbots and AI-based conversational agents have emerged as promising tools for mental health screening and assessment.…
Subject-independent classification of ADHD from pediatric EEG: a leakage-aware deep learning framework with interpretable neurophysiological mapping
BackgroundThe use of electroencephalography (EEG) in automated screening of Attention-Deficit/Hyperactivity Disorder (ADHD) has created a large body of literature that suggests promising outcomes, with reported classification accuracies often above 90%. A major methodological issue suggests that a substantial part of…

