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465 results

Vitamin A status is associated with sleep, clock genes, and symptoms in children with autism spectrum disorder

BackgroundVitamin A signals through retinoic acid receptors and may influence neurodevelopment and the expression of clock genes. However, the biological pathway linking vitamin A status to sleep disturbance in ASD remains insufficiently defined. This study aimed to examine associations between…

Tags: Academic research, Autism, Epigenomics, Sleep and arousal regulation

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Methylome-Wide Association Study of Obsessive-Compulsive Disorder

Obsessive-compulsive disorder (OCD) is a debilitating psychiatric condition influenced by both genetic and environmental risk factors. Epigenetic modifications, such as DNA methylation, may offer insights into biologically meaningful differences associated with the disorder.

Tags: Academic research, Epigenomics, OCD

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It Is the Journey, Not the Destination: Moving From End Points to Trajectories When Assessing Chatbot Mental Health Safety

Large language models are rapidly becoming embedded in everyday life through artificial intelligence (AI) chatbots that people use for practical assistance and companionship, as well as for support with mental health and emotional wellbeing. Alongside clear benefits, clinicians and public…

Tags: Academic research, Cognitive focus and executive control, Mental health, Sleep and arousal regulation

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Tags: Academic research, Depression, Mood and emotional regulation

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The Unspoken Toll: Why Exam Pressure Must Be Part of the Youth Mental Health Discussion

A Conversation with Tatum Redmond and Amanda van der Vyver-Anderson from Community Keepers, South Africa By Mai El Shoush, Partnerships Campaign Manager, Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute Community…

Tags: Academic research, Anxiety, Charity / nonprofit, Cognitive focus and executive control, Depression, Mental health, Mood and emotional regulation

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Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis: A Micro-Randomized Trial

Conditions: Psychosis; Anxiety; Depression; Rumination Interventions: Behavioral: Smartphone-based Mindfulness Exercise; Behavioral: Smartphone-based Psychoeducation; Behavioral: Neutral Control Message Sponsors: Mclean Hospital Not yet recruiting

Tags: Academic research, Anxiety, Clinical trial, Mental health, Mood and emotional regulation, Reality testing and perceptual stability, Schizophrenia spectrum

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GLP-1 Receptor Agonists in Psychiatry: A Pharmacoepidemiological Scoping Review

Pharmacoepidemiological studies have expanded the capacity to detect therapeutic benefits and adverse drug effects of medications. In the case of glucagon-like peptide-1 receptor agonists (GLP-1RAs), their fast uptake for treating diabetes and obesity has generated substantial real-world experience, facilitating exploration…

Tags: Appetite and ingestive regulation, Medication, Mental health

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AI Chatbots for Mental Health Self-Management: Lived Experience–Centered Qualitative Study

Background: Large language models (LLMs) now enable chatbots to engage in sensitive mental health conversations, including depression self-management. Yet their rapid deployment often overlooks how well these tools align with the priorities of people with lived experiences, which can introduce…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation, Social and attachment drive

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Tags: Clinical trial, Depression, Mood and emotional regulation

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Impact of abnormal metabolic-immunoinflammatory pathway on splenomegaly in patients with chronic schizophrenia and exploration of risk factors: case-control study

ObjectiveThis study aimed to identify risk factors for splenomegaly in chronic schizophrenia patients and clarify associations among metabolic−immunoinflammatory pathways, psychiatric symptoms and splenomegaly. The findings will help optimize somatic monitoring and intervention strategies.MethodsA case−control design was used. A total of…

Tags: Academic research, Medication, Mood and emotional regulation, Schizophrenia spectrum

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