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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Bone Density Linked with Brain Function
Lower bone density is linked with worse cognitive function, which may help identify postmenopausal women at risk of parallel skeletal and neurologic decline. The post Bone Density Linked with Brain Function appeared first on Inside Precision Medicine.
The Importance of Intergenerational Dialogue
How the Stavros Niarchos Foundation (SNF) Global Center’s second annual Global Summit on Youth Mental Health is advancing opportunities for young people and experts to exchange perspectives and shape priorities together. The post The Importance of Intergenerational Dialogue appeared first…
Pilot evaluation of an educational and lived experience training program on ketogenic metabolic therapy in mental health care for health care professionals
BackgroundSerious mental illness imposes a substantial burden. Pharmacologic treatments remain only partially effective and are associated with significant side effects, highlighting the need for novel treatment approaches. Ketogenic metabolic therapy (KMT) is emerging as an intervention for serious mental illness,…
Neural mechanisms of uncertain decision-making in anxious adolescents: an EEG study based on the balloon analogue risk task
BackgroundAdolescence is marked by heightened vulnerability to anxiety which can impair decision-making under uncertainty. The underlying neural oscillatory network-level mechanisms in anxious adolescents require further elucidation.MethodsWe recruited 40 adolescents (20 adolescents with clinically diagnosed anxiety disorders, 20 matched controls). Participants…
Methamphetamine-withdrawal catatonia resolved with mixed amphetamine salts: a case report
Catatonia is a well-recognized psychiatric emergency with an evolving understanding of its underlying pathophysiology. However, withdrawal-associated catatonia remains poorly characterized. Here we describe a 32-year-old man with symptoms consistent with methamphetamine-withdrawal catatonia, a previously undescribed etiology, which resolved only after…
New federal autism committee head has financial ties to leucovorin
RFK Jr. has installed John Gaitanis, a pediatric neurologist, as the new chair of the Interagency Autism Coordinating Committee, which helps the federal government decide how to allocate roughly $2 billion…
A Comparison of Group Cognitive Behavioural Therapy (CBT) and Structured Activity Group for Adults With Attention Deficit Hyperactivity Disorder (ADHD)
Conditions: ADHD Interventions: Behavioral: Group CBT based on DBT-skills training; Behavioral: Activity group Sponsors: Region Stockholm Recruiting
ADEPT Psilocybin-Assisted Therapy With DBT for Borderline Personality Disorder
Conditions: Borderline Personality Disorder; Borderline Personality Pathology; Depressive Symptoms; Emotion Dysregulation; Suicidal Ideation Interventions: Drug: Psilocybin; Behavioral: Psilocybin-Assisted Therapy With Dialectical Behavior Therapy Sponsors: University of Minnesota; Filament Health Corp. Not yet recruiting
Supporting the Primary Outcomes of the Mirai Trial for the Adjunctive Digital Therapeutic Rejoyn (CT-152) in the Treatment of Major Depressive Disorder: Meaningful Change Analysis in the Montgomery-Åsberg Depression Rating Scale
Background: Rejoyn (CT-152) is a prescription digital therapeutic (DTx) adjunct to antidepressive medication authorized for patients with major depressive disorder. To better understand the patient benefit of DTx and other treatment modalities, current regulatory standards support the use of modern…
Agreement Between a Mobile Self-Administered Comprehensive Geriatric Assessment Screening Tool and Geriatrician-Administered Assessment: Cross-Sectional Feasibility Study
Background: Comprehensive geriatric assessment (CGA) is a widely recommended, multidimensional approach for guiding clinical decision-making and management in older adults. However, its implementation remains limited by a shortage of geriatric specialists, the complexity of geriatric care, and the increasing demands…
STAT+: Pharmalittle: We’re reading about Novo plans to expand its pipeline, early Alkermes ADHD data, and more
Novo Nodisk outlined plans to expand its pipeline and find new products that it could sell more like consumer goods than traditional medicines
Looking Ahead to the SNF Global Center’s Second Annual Global Summit on Youth Mental Health
As mental health care, education, and research for youth advances, it is important to remember that in order to best serve young people, we must listen to their lived experience. The post Looking Ahead to the SNF Global Center’s Second…
Ultrasound neuromodulation in brain disorders: from mechanotransduction mechanisms to clinical translation
Brain disorders impose a major global health burden, yet current pharmacological and neuromodulation therapies are often constrained by invasiveness, limited spatial precision, poor access to deep brain structures, or insufficient long-term efficacy. Non-invasive ultrasound neuromodulation has emerged as a promising…
Efficacy of a personalized, response-based transdiagnostic intervention for emotional disorders delivered via the Internet: a protocol for an adaptive randomized controlled trial
One of the main challenges in clinical psychotherapy is disseminating effective psychological treatments to the millions who need them but lack access. Transdiagnostic interventions, particularly those delivered online, can help bridge this treatment gap. However, these interventions, often provided as…
Parental depressive symptoms and shared reading practices among preschool children in western China: cross-sectional study
BackgroundShared reading supports early child development, but parental depressive symptoms may reduce its frequency and quality. Most previous studies assumed linear relationships with small samples. This large cross-sectional study examined linear and non-linear associations between parental depressive symptoms and shared…
Body image dissatisfaction and emotional eating across age and weight status: a comparative cross-sectional study
BackgroundObesity in older adults is associated with significant medical, functional, and psychological consequences, including body image dissatisfaction and maladaptive eating behaviors such as emotional eating. Although these associations have been extensively studied in younger populations, limited evidence is available in…
Possible drivers of self-harm severity – relative contributions of post-traumatic stress and levels of personality functioning – results from the Extreme Challenges project
BackgroundSelf-harm (SH) is common, but its severity varies. Severe cases may involve extensive hospitalization and high suicide risk. Although SH is associated with post-traumatic stress disorder (PTSD), personality disorder (PD), and complex cases of PD-PTSD comorbidity, factors related to SH…
STAT+: Alkermes’ orexin agonist shows potential to treat ADHD in early-stage trial
The drugmaker Alkermes said a therapy called an orexin agonist for the first time showed potential to treat people with ADHD in an early-stage study.
Study on the Prevention of Weight Loss Through Physical Activity Among Nursing Home Residents
Conditions: Appetite Loss in Aging; Anorexia of Aging Interventions: Other: Physical activity; Other: Appetite assessment; Other: Food intake assessment; Other: Assessment of the efficiency; Biological: Blood test at baseline; Biological: Blood test at the end of the study; Other: Functional…