Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Attachment and Substance Use Disorder: An Interventional Study in an Addictology Day Hospital
Conditions: Addiction Disorders Interventions: Behavioral: attachment-focused therapeutic program; Behavioral: psychoeducation-based intervention (standard care) Sponsors: Centre Hospitalier de Cadillac Completed
A comparative study of traditional Chinese mind-body therapies on sleep quality, mental health, and quality of life in patients with sleep disorders: a network meta-analysis based on randomized controlled trials
BackgroundSleep disorders are a common clinical condition characterized primarily by difficulty falling asleep, trouble maintaining sleep, and impaired daytime functioning, with a high prevalence among adults. This condition can lead to a persistent decline in sleep quality, trigger mental health…
Palomar Labs Spins Out Ariadne Bio to Advance Non-Hallucinogenic Therapy for Parkinson’s Apathy
Backed by preclinical data and funding from The Michael J. Fox Foundation, Ariadne Bio is advancing AB-300, a serotonin 2A receptor agonist, as a potential treatment for Parkinson’s-related apathy. The post Palomar Labs Spins Out Ariadne Bio to Advance Non-Hallucinogenic…
Strategies to enhance engagement in CBT for adult ADHD: an innovation tournament with stakeholders
ObjectiveAdults with ADHD report challenges engaging in cognitive-behavioral therapy (CBT). This study investigates practices that might be applied to improve intervention fit and therapeutic engagement of CBT for adults with ADHD.MethodWe conducted an Innovation Tournament (IT) and member checking with…
School refusal behavior in children and adolescents: a concept analysis
School refusal behavior (SRB) is increasingly recognized across educational, pediatric, and mental health settings, yet its conceptual boundaries remain unclear, and the term is frequently conflated with school refusal, truancy, school withdrawal, school exclusion, and broader school attendance problems. This…
Predicting multiple mental health outcomes in adolescents using explainable machine learning models
IntroductionAdolescent mental health problems, including depression, anxiety, and stress, are an increasing public health concern, yet the factors associated with different mental health outcomes may vary across domains. This study investigated shared and outcome-specific predictive features of depression, anxiety, perceived…
Resting-state frontal theta/beta ratio and psychological symptoms in college students: an EEG study
BackgroundMental health problems are increasingly prevalent among college students and represent an important public health concern. Neurophysiological indicators derived from electroencephalography (EEG) may provide objective markers for identifying psychological vulnerability. The theta/beta ratio (TBR) has been widely associated with attentional…
How genes shape personality and experience
Nature Medicine, Published online: 18 September 2026; doi:10.1038/d41591-026-00046-yA genome-wide association study involving over one million people reveals genetic contributions to personality traits, with potential causal effects on physical and mental health and behaviors.
Interventional rTMS for Improving Social Perception in Autism
Conditions: Autism Spectrum Disorders (ASD) Interventions: Device: Neuromodulation by transcranial magnetic stimulation (TMS); Radiation: Anatomo-functional MRI; Device: Eye-tracking; Other: Social Responsiveness Scale, Second Edition (SRS-2) Sponsors: Assistance Publique - Hôpitaux de Paris; URC-CIC Paris Descartes Necker Cochin Not yet recruiting
The BRAVE (Behaviourally Responsive Assessments of Vital Signs in Emergency) Study
Conditions: Autism Spectrum Disorder Interventions: Device: wearable vital sign device Sponsors: Hamilton Health Sciences Corporation Not yet recruiting
Dual-task standing in older adults with mild cognitive impairment: postural control complexity, prefrontal activation, and cognitive task performance
BackgroundThis study aimed to quantify prefrontal cortex (PFC) activation and postural control complexity in older adults with mild cognitive impairment (MCI) during single-task standing and dual-task standing balance conditions and to investigate the associations between these measures.MethodsThis secondary analysis included…
Daytime lighting conditions alter home-cage behavior across both sexes in diurnal grass rats
Circadian rhythms are crucial to biological functions, and cognitive functions such as attention, choice, and preference-related behaviors are modulated by circadian rhythms and disrupted in mood disorders such as Seasonal Affective Disorder (SAD) and Major Depressive Disorder (MDD). These neuropsychiatric…
Exploratory cluster analysis of self-reported adverse events associated with antidepressants using Gower distance and partitioning around medoids: a single-center cross-sectional study
BackgroundAntidepressants are first-line pharmacological interventions for depressive disorders, with globally increasing prescription volumes. Associated adverse events (AEs) represent the primary reason for treatment discontinuation. Existing studies mostly limit analysis to simple stratification by organ system or severity, while exploratory subtyping…
PROMATER: protocol for a randomized controlled trial of a digital self-guided intervention to promote perinatal mental health and reduce self-criticism
BackgroundPerinatal mental health represents a significant public health concern given the high prevalence of mental disorders during pregnancy and the postpartum period and their impact on maternal well-being, mother-infant bonding, and child development. Emerging evidence identifies self-criticism as a transdiagnostic…
Association between first-trimester serum 25(OH)D and EPDS-positive postpartum depressive symptoms in women with gestational diabetes mellitus: a retrospective cohort study
IntroductionGestational diabetes mellitus (GDM) has been associated with an increased risk of postpartum depressive symptoms, while maternal vitamin D status may also be related to perinatal mood disturbances. This study investigated the association between first-trimester serum 25-hydroxyvitamin D [25(OH)D] concentrations…
Body-based therapies and transcranial magnetic stimulation for posttraumatic stress disorder: a proposed integrative approach
Posttraumatic stress disorder (PTSD) remains difficult to treat, with 30–50% of patients retaining their diagnosis after first-line trauma-focused psychotherapies. Body-based therapies (BBTs) and transcranial magnetic stimulation (TMS) have each shown preliminary benefit for PTSD but have not yet been studied…
Perinatal mental health equity: patient perspectives on virtual collaborative care providing what women need now in the post-COVID era
IntroductionThe COVID-19 pandemic increased perinatal mental health needs and disrupted routine obstetric care, disproportionately affecting Black and economically disadvantaged communities. Michigan’s Perinatal Collaborative Care Model (Peri CoCM), a publicly funded virtual program, launched during the pandemic and continued after the…
Problematic Reliance on Generative AI in an Anxious Young Adult: Case Report
Generative Artificial Intelligence (AI) tools are increasingly integrated into daily life, offering cognitive support across domains such as writing, decision-making, and social interpretation. While beneficial, excessive reliance may contribute to diminished confidence in one’s own thinking. This report describes a…
Caregiver Challenges and Functional Requirements for an mHealth App Supporting Home-Based Dementia Care: Qualitative Interview Study
Background: The growth of the older adult population in Indonesia since 2019 has contributed to a 2.46% increase in dementia cases, with the number of cases projected to increase 2.5-fold by 2050. This trend is exerting a major impact on…
Brain Protein in Mice Offers Insights Into Brain Development and ADHD
Researchers identified a brain protein, NSF, that is important for maintaining dopamine-related cells and normal development, providing new insights into ADHD and potential therapeutic strategies. The post Brain Protein in Mice Offers Insights Into Brain Development and ADHD appeared first…