Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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The race for an Ebola therapy begins
Male marathoners "hit the wall," mental health in 2026, and more Morning Rounds news
Biomarkers Could Help in Antidepressant Choice
Biomarkers could help identify people with depression who would gain most from treatment with a selective serotonin reuptake inhibitor and those who would do better with another medication. The post Biomarkers Could Help in Antidepressant Choice appeared first on Inside…
South Korea’s hottest new bachelors are chip workers
Baek, a 35-year-old manager at the South Korean semiconductor titan SK Hynix, was enrolled in Sunoo, a matchmaking company based in Seoul, a year ago. In a move typical of anxious South Korean parents, his mother signed him up, hoping…
Impact of Short and Mistimed Sleep on Adolescents With ADHD: The Adolescent Attention and Circadian Timing Study
Conditions: ADHD Interventions: Behavioral: Aligned sleep extension; Behavioral: Misaligned sleep extension Sponsors: Children's Hospital Medical Center, Cincinnati; National Institute of Mental Health (NIMH) Not yet recruiting
Diagnostic Accuracy and Safety of the Attention-Deficit/Hyperactivity Disorder Auxiliary Evaluation System (AHEF) in Chinese Children Aged 6 to 12
Conditions: Attention-Deficit; Hyperactivity Disorder Interventions: Diagnostic Test: AHEF Sponsors: Chongqing Jinsaixing Medical Technology Co., Ltd Not yet recruiting
MH-POWER for College Students on the Spectrum
Conditions: College Students on the Autism Spectrum With Mental Health Challenges Interventions: Behavioral: The MH-POWER program Sponsors: University of Texas Rio Grande Valley; The American Occupational Therapy Foundation Recruiting
Efficacy of “DBT-LIVE”, an Identity Skills Training Program, for Borderline Personality Disorder.
Conditions: Treatment 1:Dialectical Behavior Therapy (DBT); Treatment as Usual Interventions: Behavioral: DBT LIVE; Behavioral: TAU Sponsors: Universidad Europea de Valencia Not yet recruiting
Email-Delivered Digital Positive Affect Intervention for Young Adults in Zimbabwe
Conditions: Depression Symptoms Interventions: Behavioral: Email-Delivered Positive Affect Intervention; Behavioral: Psychoeducational Control Sponsors: Vilnius University; University of Zimbabwe Not yet recruiting
Effect of Cognitive Behavioral Based Psychoeducation Program on Internet Addiction and Academic Procrastination Tendency in Nursing Students
Conditions: Internet Addiction; Procrastination Interventions: Behavioral: Cognitive Behavioral Approach-Based Psychoeducation Program Sponsors: Saglik Bilimleri Universitesi Completed
Virtual Reality–Based Relaxation Training and Symptom Improvement Among Inpatients With Depressive Disorders: Retrospective Nonrandomized Comparative Study
Background: Virtual reality (VR) is increasingly used for adjunctive relaxation training in psychiatric care. However, evidence remains limited among hospitalized patients with depressive disorders, particularly in routine inpatient settings in China, and little is known about whether improvement varies by…
Digital Cognitive Behavioral Therapy for Older Adults With Symptoms of Depression: Feasibility Cohort Study
Background: Depressive symptoms are common among older adults and can significantly impact their quality of life. However, many older adults face barriers to accessing psychological treatment. Internet-based cognitive behavioral therapy (iCBT) is a promising alternative to face-to-face treatments, but its…
“Mirror, mirror, on the wall, without you, I will fall”: investigation into body dysmorphic disorder from an attachment perspective
ObjectiveBody dysmorphic disorder (BDD) is a prevalent concern among young adults. However, the underlying mechanisms of BDD development remain elusive. This study aims to investigate the intricate relationship between attachment styles and BDD symptoms, with appearance-based rejection sensitivity (ARS) as…
Intranasal esketamine plus oral antidepressant for treatment-resistant depression: acute induction and maintenance relapse-prevention outcomes in a systematic review and meta-analysis
Treatment-resistant depression (TRD) remains a major clinical challenge. Intranasal esketamine, used adjunctively with an oral antidepressant, has been evaluated in randomized trials, but uncertainty persists regarding the magnitude and consistency of benefit, durability, and key harms. This systematic review and…
Exercise interventions are most consistently supported for depressive disorders: an umbrella review of diagnosed depressive and anxiety disorders
BackgroundExercise is increasingly discussed as part of lifestyle-based and multimodal care for mood and anxiety disorders, but review-level evidence often mixes formally diagnosed clinical populations with symptom-defined or medically mixed samples.MethodsWe conducted an umbrella review of systematic reviews, meta-analyses, and…
Health outcomes across socioeconomic strata B, C, and DE among Brazilian adults living in moderate social vulnerability
ObjectivesThis study examined whether socioeconomic status was associated with anxiety symptoms, depressive symptoms, BMI, waist-to-hip ratio, and quality of life among Brazilian adults living in areas of moderate social vulnerability. In addition, we described anxiety and depressive symptoms, BMI and…
Effects of Virtual Reality on Postoperative Pain Management Following Minimally Invasive Gynecologic Surgery: Randomized Controlled Trial
Background: Postoperative pain and anxiety remain common concerns after minimally invasive gynecologic surgery despite advances in surgical techniques and analgesic strategies. Virtual reality (VR) has been investigated as a potential nonpharmacological intervention for pain management; however, evidence in gynecologic postoperative…
From Alliance to Nexus: Rethinking Digital Therapeutic Relationships
In traditional human psychotherapy, the therapeutic alliance (TA) is regarded as a fundamental factor that describes the client-therapist relationship, mainly due to strong evidence demonstrating its impact on treatment outcomes regardless of theoretical orientation. More recently, advances in artificial intelligence…
Prediction of Clinically Significant Depressive Symptoms at 2-Year Follow-Up in Older Adults: Machine Learning Study Using the English Longitudinal Study of Ageing
Background: Depression in older adults is often underdiagnosed due to atypical symptom presentation and generational stigma, leading to delayed intervention. Early identification of individuals at risk of developing elevated depressive symptoms is therefore critical, but traditional approaches show limited predictive…
EFE-8c4, a polyamine from Elaeagnus multiflora, protects neuronal cells by regulating oxidative stress and apoptotic pathways
Neurological disorders, including depression, cognitive impairment, and neurodegenerative diseases, are closely associated with oxidative stress, apoptotic neuronal loss, and impaired neuronal differentiation. Polyamine derivatives from natural products have emerged as potential neuroprotective agents, although their mechanisms remain incompletely understood. In…
Developing forensic patient-oriented research guidelines: a rapid review using an integrated knowledge translation approach
This paper reports findings from a rapid literature review that informed new guidelines for conducting patient-oriented research in forensic mental health settings. The project adopted an integrated knowledge translation approach at a mental health hospital in Ontario, Canada, engaging a…