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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Heat waves mess with your brain. Scientists are trying to figure out why.
It’s been hot in London this week. Really hot. A dangerous heat wave has hit Western Europe. Yesterday, the UK recorded its highest ever June temperature at 36.1 °C (about 97 °F). But as the weather app on my phone…
A Pilot Study of Adjunctive Structured Supportive Psychotherapy in Schizophrenia
Conditions: Schizophrenia; Cognitive and Executive Dysfunction; Neuroinflammation Interventions: Behavioral: Structured supportive psychotherapy; Drug: Risperidone 2 mg; Behavioral: Standard Clinical Care with Active Control; Drug: Risperidone 2 mg Sponsors: Hasanuddin University Completed
Young Adults’ Perspectives on an Ecological Momentary Intervention for Drinking to Cope: Qualitative Study
Background: Young adults have high rates of mental health problems, such as mood or anxiety symptoms, and high rates of problematic drinking. Many young adults who undergo psychiatric hospitalization to address depression and anxiety symptoms also engage in risky drinking…
Mental Illness Shows Context-Specific Genetic Effects
Many DNA variants that do not encode proteins and are linked with neuropsychiatric diseases such as schizophrenia depend on neuronal activation, suggesting that the genetics of brain disorders may depend on context. The post Mental Illness Shows Context-Specific Genetic Effects…
Angry Kids: Dealing With Explosive Behavior
When a child — even a small child — melts down and becomes aggressive, they can pose a serious risk to themselves and others, including parents and siblings. It’s not uncommon for kids who have trouble handling their emotions to…
Bipartisan bill seeks to allow direct prescribing of methadone for opioid addiction
Methadone for opioid addiction has been available only at specialty clinics. A bipartisan bill would greatly expand access.
Associations between childhood trauma, intolerance of uncertainty, and symptom severity in obsessive-compulsive disorder
BackgroundChildhood trauma (CT) has been associated with obsessive-compulsive disorder (OCD), but its relationship with obsessive-compulsive symptom (OCS) severity remains inconsistent. Intolerance of uncertainty (IU) may represent one of the cognitive processes underlying this association. The present study aimed to examine…
Coproduction Without Youth? Closing the Participation Gap in Digital Mental Health Research
Young people are among the most intensive users of digital and generative artificial intelligence (GenAI)–enabled mental health tools, yet they remain underrepresented in the research and design processes that shape these technologies. Although participatory approaches such as co-design and patient…
Supporting Student Mental Health With the Safespace Generative AI Chatbot: Mixed Methods Feasibility Study
Background: Generative artificial intelligence (GenAI) chatbots have the potential to provide personalized mental health support to individuals at scale. Objective: This study evaluates the feasibility and usage patterns of the Safespace GenAI chatbot, an artificial intelligence (AI)–driven smartphone app that…
Global research landscape, knowledge structure, and emerging trends in adverse childhood experiences and personality disorders: a bibliometric analysis
BackgroundThe relationship between adverse childhood experiences (ACEs) and personality disorders (PDs) has attracted sustained attention in psychiatry, psychology, and public health. Existing studies have mainly examined epidemiological associations, specific PDs diagnoses, or mechanisms, whereas bibliometric evidence mapping the field’s knowledge…
Shared reading is associated with fewer emotional/behavioral problems and better prosocial behavior in preschool children: a cross-sectional study in western China
BackgroundThe home literacy environment, particularly shared reading, plays a critical role in preschool children’s cognitive and socioemotional development. However, its associations with emotional and behavioral problems remain underexplored in large-scale studies. This study examined the relationship between shared reading and…
Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in Children
Conditions: Attention Deficit Hyperactivity Disorder Interventions: Dietary Supplement: Inulin; Dietary Supplement: Probiotic; Dietary Supplement: Omega-3 Fatty Acids; Dietary Supplement: Thiamine; Other: Placebo Sponsors: Khyber Medical University Peshawar; Khyber Teaching Hospital Recruiting
Virtual Reality Headset as an Alternative Tool for Reducing Dental Anxiety
Conditions: Neurodevelopmental Disorder (Diagnosis) Interventions: Device: Virtual reality headset; Other: standard dental care Sponsors: Semmelweis University Enrolling by invitation
Dynamic changes of gut microbiota during progression of three Alzheimer’s disease mice models
IntroductionAlzheimer’s disease (AD) is an age-related and progressive neurodegenerative disorder characterized by cognitive impairment and irreversible neuronal degeneration, affecting approximately 55 million individuals worldwide. Despite extensive research efforts, the underlying pathogenic mechanisms of AD remain incompletely understood, and effective therapeutic…
Applications of machine learning algorithms to detect digital addiction: a meta-analysis
Digital addiction (DA) has emerged as a significant global concern, yet traditional diagnostic methods relying on self-report questionnaires face subjective bias and threshold inconsistencies. Recent advances in machine learning (ML) offer promising alternatives for automated DA detection. This study conducted…
Gender-specific symptom outcomes on cariprazine treatment: a 12-month naturalistic longitudinal follow-up study in schizophrenia
IntroductionA growing body of literature is focusing on third-generation antipsychotics and their unique characteristics, but few studies have examined gender as a crucial factor in response profiles. The present study aims to address this gap by analyzing the outcomes of…
Evaluation of Benign Joint Hypermobility and Serum Prolidase Levels in Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (ADHD) Compared to Healthy Controls
Conditions: ADHD; Benign Joint Hypermobility Syndrome; ADHD - Attention Deficit Disorder With Hyperactivity; ADHD - Combined Type; ADHD - Inattentive Type Sponsors: Antalya Training and Research Hospital Completed
4-STEP-Training Program for Doomscrolling, Cyberchondriac Behavior and Psychiatric Symptoms (4-STEP-TPS) Among Individuals With Social Media Addiction
Conditions: Doomscrolling; Cyberchondriac Behavior; Social Media Addiction Interventions: Behavioral: 4-STEP-Training Program for Social Media Addiction (4-STEP-TPS) Sponsors: Government College University Faisalabad Not yet recruiting
Dog-Assisted Therapy in Adolescents Attending a Child and Adolescent Mental Health Day Hospital
Conditions: Mental Health Disorders in Adolescents; Emotional Dysregulation; Anxiety Disorders; Depressive Disorders; Eating Disorders Interventions: Behavioral: Experimental: Experimental: Dog-assisted therapy + Treatment as usual; Other: Active Comparator: Treatment as usual Sponsors: Hospital Clinic of Barcelona; Obra Social La Caixa, Spain…
Long‑Range Gene Networks Uncover 641 New Schizophrenia‑Associated Genes
A new gene‑network modeling framework integrating cis and trans regulatory effects identifies 766 schizophrenia‑associated genes—641 previously missed—across six brain regions. The post Long‑Range Gene Networks Uncover 641 New Schizophrenia‑Associated Genes appeared first on GEN - Genetic Engineering and Biotechnology News.