Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Synaptic remodeling and the female depression exposome: a mini-review of neuroendocrine, epigenetic, and social determinants
Depression is a multifactorial, chronic disorder and represents a leading cause of disability, with women exhibiting nearly twice the lifetime prevalence compared to men. Growing evidence indicates that this disparity cannot be explained by hormonal or psychosocial factors, but rather…
Stage-specific ERP correlates of audiovisual facial emotion processing across depressive tendencies
Emotional dysregulation can emerge as early as the initial stages of depression. This study aimed to examine event-related potential characteristics during the perception of negative, positive, and neutral facial expressions in healthy individuals across depressive tendencies. Twenty-six healthy participants underwent…
Analysis of the prevalence of dyslipidemia in early-onset schizophrenia patients and its correlation with clinical characteristics
ObjectiveTo analyze the prevalence of dyslipidemia and related influencing factors in patients with early-onset schizophrenia (EOS).MethodsWe recruited 289 pediatric and adolescent EOS patients from October 2021 to June 2024 in the Third People’s Hospital of Fuyang. Researchers gathered comprehensive demographic…
Esketamine ameliorates depression-like behavior in mice via modulation of the NRG1–ErbB4 pathway
BackgroundEsketamine has a significant and rapid antidepressant effect. Although studies have shown that Neuregulin 1 (NRG1) and it’s signaling pathway are associated with depression, the possible regulatory relationship of esketamine on the NRG1-ErbB4 pathway is not yet clear.MethodsTo induce depressive-like…
Vitamin A status is associated with sleep, clock genes, and symptoms in children with autism spectrum disorder
BackgroundVitamin A signals through retinoic acid receptors and may influence neurodevelopment and the expression of clock genes. However, the biological pathway linking vitamin A status to sleep disturbance in ASD remains insufficiently defined. This study aimed to examine associations between…
Methylome-Wide Association Study of Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) is a debilitating psychiatric condition influenced by both genetic and environmental risk factors. Epigenetic modifications, such as DNA methylation, may offer insights into biologically meaningful differences associated with the disorder.
pBFS Guided Neuromodulation Over DMPFC for ASD Treatment: Pilot Study
Conditions: Autism Spectrum Disorder With Language Delay Interventions: Device: active iTBS Sponsors: Changping Laboratory; China Rehabilitation Research Center; Henan Provincial People's Hospital Completed
Mobile Health Intervention for Children With Autism: A Randomized Clinical Trial
Conditions: Autism Spectrum Disorder; Obesity; Pediatric Overweight Interventions: Behavioral: Standard Lifestyle Recommendations; Behavioral: WeChat-Based Mobile Health Intervention; Behavioral: Coach-Facilitated Tele-Group Sessions Sponsors: Hunan Normal University Completed
The Most Effective OCD Treatment Reaches Almost No One: Here’s What We Can Do About It
– Rebecca Deusser, MS, MBA and Sanjaya Saxena, MD “It took me years to find out that what I was dealing with was OCD!” This is a phrase all too... Read more » The post The Most Effective OCD Treatment…
It Is the Journey, Not the Destination: Moving From End Points to Trajectories When Assessing Chatbot Mental Health Safety
Large language models are rapidly becoming embedded in everyday life through artificial intelligence (AI) chatbots that people use for practical assistance and companionship, as well as for support with mental health and emotional wellbeing. Alongside clear benefits, clinicians and public…
Opinion: When my child is in psychosis, the pediatric health care system can’t help us
“There is no off switch when the crisis is your child,” writes Liz Koch.
Effectiveness of Hatha Yoga and From Feeling to Seeing the Body (FSB) in Female Adolescents and Young Adults With Eating Disorders.
Conditions: Body Image; Eating Disorders; Anorexia Nervosa; Bulimia Nervosa Interventions: Behavioral: Hatha Yoga Group (Y); Behavioral: From Feeling to Seeing the Body Group (FSB); Behavioral: Control Group (C) Sponsors: Azienda Ulss 2 Marca Trevigiana Completed
Social cognitive deficits and altered multi-brain dynamics during problem-solving in heroin abstainers: An fNIRS hyperscanning study
Despite extensive research on the neurobiology of addiction, little is known about how repeated drug use and withdrawal are related to social functioning impairments in humans, a highly social species. This obscures the broader societal impact of drug addiction and…
Long Term Follow-up of Mentalization-Based Treatment: Exploring Variability in Outcomes, Long-term Value and Experiences 10+ Year After Receiving MBT Day Hospital or MBT Intensive Outpatient
Conditions: Borderline Personality Disorder Sponsors: De Viersprong; Arkin Not yet recruiting
Impact of an Educational Program on Teachers’ Knowledge and Classroom Performance Regarding ADHD
Conditions: ADHD - Attention Deficit Disorder With Hyperactivity Interventions: Behavioral: ADHD Educational Program for Primary School Teachers Sponsors: Dlniya Ismail Rashid Active, not recruiting
Research on the Molecular Mechanism of Cognitive Differences Between Williams Syndrome and Autism Spectrum Disorder
Conditions: Williams Syndrome; Autism Disorder Sponsors: Qilu Hospital of Shandong University Not yet recruiting
The Unspoken Toll: Why Exam Pressure Must Be Part of the Youth Mental Health Discussion
A Conversation with Tatum Redmond and Amanda van der Vyver-Anderson from Community Keepers, South Africa By Mai El Shoush, Partnerships Campaign Manager, Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute Community…
Pilot Study of Sensor-Informed Smartphone-based Mental Health Interventions for Mood in Early Psychosis: A Micro-Randomized Trial
Conditions: Psychosis; Anxiety; Depression; Rumination Interventions: Behavioral: Smartphone-based Mindfulness Exercise; Behavioral: Smartphone-based Psychoeducation; Behavioral: Neutral Control Message Sponsors: Mclean Hospital Not yet recruiting
Safety Planning Intervention for Autistic Youth: A Randomized Controlled Trial With Providers in Developmental-Behavioral Pediatric Clinics
Conditions: Autism; Suicide Prevention Interventions: Behavioral: Safety Planning Intervention; Behavioral: Crisis Interventions for Pediatric Providers - Autism version (CIPP-A) Sponsors: Children's Hospital Los Angeles; Children's Hospital of Philadelphia Not yet recruiting