Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Gene Therapy Restores Brain Function and Behavior in Fragile X Syndrome
An AAV-based therapy carrying a normal human version of the FMR1 gene to produce the Fragile X messenger ribonucleoprotein (FMRP) found that early treatment normalized several measures of brain activity while improving social behavior, exploratory behavior, and cognitive flexibility. The…
Functional Outcome Prediction in Young Adults With Mental Health Symptoms Using Machine Learning and Large Language Models: Longitudinal Observational Study
Background: Functional impairments associated with mental health conditions are on the rise. Predicting functional outcomes may improve the targeting of preventive interventions. While prognostic models have primarily focused on psychosis, early recognition services require a transdiagnostic approach. Objective: This study…
When OCD Is Loud, Trust Your Higher Power
by Annabella Hagen, LCSW When I met Marie, she shared how faith and her connection with a Higher Power had always been important in her life. Her parents taught her... Read more » The post When OCD Is Loud, Trust…
The Role of Gender in Borderline Personality Disorder
Conditions: Borderline Personality Disorder (BPD) Sponsors: University Hospital Heidelberg Recruiting
Network analysis of spousal support and fear of childbirth in pregnant women of advanced maternal age
BackgroundFear of childbirth is an important perinatal mental health concern, particularly among women of advanced maternal age. However, the specific interrelations between spousal support and fear of childbirth remain unclear.MethodsThis cross-sectional study recruited 279 pregnant women of advanced maternal age…
Psychotherapy initiation is associated with discontinuation of psychotropic medications without dose escalation: a ten-year real-world cohort study (2014-2024)
BackgroundIncreasing psychotropic prescribing has raised concerns about long-term safety and regimen complexity in mental health care. Although psychotherapy is an established treatment, its role in medication optimization and psychotropic medication reduction in real-world practice across patient subgroups remains insufficiently characterized.ObjectiveTo…
Cognitive-attitudinal factors predict CBT-I enrollment willingness in Chinese sleep clinic patients: a knowledge-attitudes-practices survey
BackgroundDespite strong evidence for cognitive behavioral therapy for insomnia (CBT-I), uptake remains constrained by poorly understood cognitive, attitudinal, and practical barriers. This study examined determinants of willingness to enroll in sleep improvement programs among adults at risk of sleep disorders—including…
Brain-Infiltrating T Cells Linked to Social Deficits in Autism Mouse Model
Brain-infiltrating γδ T cells accumulate in a genetic autism mouse model, contributing to social deficits. Removing or blocking these immune cells improved sociability, highlighting immune dysregulation as a potential therapeutic target. The post Brain-Infiltrating T Cells Linked to Social Deficits…
QAIAx (AIhealth4U) – AI Public Health Central: Microcity-A (re Quantum AI Agency Aka AI City Hall Project, UPSTO App Nos. 64/074,526, 64/063,557, 63/903,181, 63/729,428
Conditions: Asperger's Disorder; Asperger Disorder; Autism Disorder; Autism; ADHD - Attention Deficit Disorder With Hyperactivity; ADHD; ASD; Alcohol Abuse/Dependence; Alcohol Addiction; Alcohol and Other Drug Use Disorders; Alcohol and Other Substance Use Prevention; Gambling Addiction; Gambling Disorder; Sex Abuse; Sex…
Designing and Evaluating a Classroom-Based Mental Health Programme for Adolescents.
Conditions: Mental Health Promotion Interventions: Behavioral: School-Based Mental Health Programme Sponsors: Queen's University, Belfast; Health Research Board, Ireland Active, not recruiting
ACT-Based Psychoeducation for Caregivers of Patients With Schizophrenia
Conditions: SCHIZOPHRENIA 1 (Disorder) Interventions: Behavioral: Acceptance and Commitment Therapy (ACT)-Based Psychoeducation Program Sponsors: Aydin Adnan Menderes University Not yet recruiting
An Acceptance and Commitment Therapy Psychoeducation Single Session Intervention on Childhood Anxiety for Carers of Children With a Long-Term Health Condition
Conditions: Long-term Health Conditions Interventions: Behavioral: Psychoeducation for anxiety Sponsors: University of East Anglia Completed
A Shared Vision for Children and Young People: Advancing Partnership and Impact at SNF Nostos 2026
Throughout the SNF Nostos 2026 week, the Child Mind Institute and the SNF Global Center for Child and Adolescent Mental Health will contribute to conversations examining how youth mental health intersects with some of today's most pressing challenges, including education,…
Smartphone-based Intervention for Young Adults With ADHD
Conditions: Attention Deficit/Hyperactivity Disorder(ADHD); Alcohol Use Interventions: Device: Ecological Momentary Assessment for ADHD and Substance Use - Intervention Group; Device: Ecological Momentary Assessment for ADHD & Substance Use - Control Group Sponsors: Traci Kennedy; National Institute on Alcohol Abuse and…
Hybrid Dialectical Behavior Therapy for Veterans to Further Reduce Emotion Regulation Problems and Trauma Symptoms
Conditions: PTSD; Emotion Regulation Disorders; Substance Abuse Interventions: Behavioral: Hybrid dialectical behavior therapy Sponsors: Arkin Recruiting
Introducing the 2026 IOCDF Award Winners of the 31st Annual OCD Conference
The mission of the International OCD Foundation — to ensure that no one affected by OCD or related disorders suffers alone — requires the collaboration and dedication of countless individuals... Read more » The post Introducing the 2026 IOCDF Award…
Turning Rejection Into a Roadmap: Advice for the Next Generation of Mental Health Leaders
Aaliyah Nadirah Madyun, program director at the Stavros Niarchos Foundation (SNF) Global Center for Child and Adolescent Mental Health at the Child Mind Institute, recently sat down with Tom Osborn, founder of the Shamiri Institute and an International Advisory Board…
EEG Biomarkers for ADHD Stimulant Treatment
Conditions: ADHD Interventions: Drug: methylphenidate HCl; Drug: Mixed amphetamine salts extended release Sponsors: Boston Children's Hospital; Seattle Children's Hospital; Tris Pharma, Inc. Not yet recruiting
Using AI to Detect Psychosis Relapse: Scoping Review
Background: Psychotic disorder represents a leading cause of disability worldwide, and relapse in psychosis is common. Artificial intelligence (AI) is increasingly recognized as a method that could aid clinical monitoring for individuals experiencing psychosis. Objective: This review aims to map…
Welcome to Our New IOCDF Advocates
The IOCDF is thrilled to announce our newest cohort of Advocate volunteers! We’re welcoming 13 incredible new Advocates to our program, bringing our total to 64 dedicated volunteers working together... Read more » The post Welcome to Our New IOCDF…