Curated research, clinical and health-technology updates relevant to the communities and partners we work with.
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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Autism service barriers for Latine children and their families: a participatory approach to adapting autism diagnostic care
IntroductionLatine children from families with limited English proficiency (LEP) experience barriers to timely autism diagnosis resulting in persistent health inequities. This participatory mixed-methods study examined these barriers and identified multi-level strategies to adapt diagnostic care models for Spanish-speaking Latine families.MethodsParticipants…
Loneliness, rumination, and adolescent psychological crisis in China: a pilot moderated mediation study
BackgroundAdolescent psychological crisis—encompassing depressive disorder, anxiety disorder, and suicidal ideation—is a major public health challenge. One in five adolescents experiences a clinically significant mental health condition globally. Loneliness is a well-documented, modifiable risk factor for these outcomes. However, the exact…
Treating addiction with an addictive drug: the ketamine paradox revisited
BackgroundSubstance use disorders (SUDs) and treatment-resistant depression (TRD) remain a major global health challenge, marked by high relapse rates and limited long-term effectiveness of existing treatments. Ketamine, a glutamatergic modulator with rapid neuroplastic effects, has emerged as a novel intervention…
Real-world outcomes of intranasal esketamine and intravenous ketamine induction therapy for treatment-resistant depression in a community clinic: a retrospective cohort study
IntroductionIntravenous (IV) ketamine and intranasal esketamine are NMDA receptor antagonists used for treatment-resistant depression (TRD). Both have demonstrated efficacy in controlled trials, but observational evidence from real-world community settings is limited.MethodsWe conducted a single-center retrospective cohort study of adults aged…
Social Cognition in Children and Adolescents With Autism Spectrum Disorder
Conditions: Autism Sponsors: Children's Hospital of Fudan University Active, not recruiting
Implementing DBT in Short-Term SUD-treatment
Conditions: Substance Abuse Disorder; Dialectical Behavior Therapy; Emotion Management Skills Interventions: Behavioral: DBT-informed milieu therapy; Behavioral: Treatment as usual Sponsors: Helse Møre og Romsdal HF Not yet recruiting
Dissociation and PTSD in women with a history of childhood sexual abuse: a pilot examination of a specialized inpatient unit
BackgroundWorldwide, there are relatively few specialized inpatient units dedicated to women with histories of childhood sexual abuse (CSA) and comorbid psychiatric disorders. This pilot study examined dissociation and PTSD among women admitted to such a specialized integrative inpatient unit in…
Resilience and Stress Among Health Care Workers Participating in the StressPal Frontline Program: Quasi-Experimental Pretest-Posttest Study
Background: Health care workers continue to experience heightened levels of distress and burnout, which contribute to higher levels of job dissatisfaction, turnover intentions, presenteeism, and staffing shortages. Objective: The aim of this study was to examine how participation in the…
Virtual Patients Will Train Future Mental Health Clinicians
The STELLAR platform will create AI-driven simulations of patients to prepare future mental health clinicians for the complexities of real-world clinical interviews. The post Virtual Patients Will Train Future Mental Health Clinicians appeared first on Inside Precision Medicine.
Impact of an Artificial Intelligence–Powered Clinical Decision Support System for Acute Kidney Injury Prevention in the Intensive Care Unit: Single-Center Uncontrolled Before-and-After Implementation Study
Background: Acute kidney injury (AKI) is a frequent and serious complication among hospitalized patients, particularly in critical care settings, where its incidence can exceed 50%. AKI is associated with increased mortality, prolonged hospitalization, dialysis dependence, and higher health care costs.…
Astrocytes Preserve Memory Persistence Through Ankyrin-2 Protein in Mice
How certain memories persist over time for learning and cognitive function remains unclear. A new study suggests that astrocytes play a critical role in long-term memory through the regulatory protein ankyrin-2 (Ank2). The post Astrocytes Preserve Memory Persistence Through Ankyrin-2 Protein in Mice appeared first…
Power without limits: exploring emotional regulation, moral authority, and psychiatric overreach through the Wizarding World of Harry Potter
BackgroundPsychiatry has never had more tools to relieve psychological suffering. Psychopharmacology, neuromodulation, early intervention, digital monitoring, and preventive approaches have expanded what clinicians can do. Yet this growing technical capacity also raises an uneasy question: when does care become control?…
Memory-focused therapy: an integrated intervention to reduce trauma symptoms, maladaptive cognitive processes, and emotional distress in Afghan youth
BackgroundAfghan youth continue to face chronic war-related trauma, terrorist violence, and severe disruptions to education and social support systems, resulting in high rates of posttraumatic stress disorder (PTSD), depression, anxiety, and hopelessness. There is a critical need for culturally responsive,…
Parental broad autism phenotype traits and executive function in families of children with autism spectrum disorder
BackgroundParents of children with autism spectrum disorder (ASD) frequently exhibit subclinical Broad Autism Phenotype (BAP) traits, though their relationship with executive function (EF) remains underexplored. This study investigated associations between parental BAP traits and their EF performance.MethodsThe Broad Autism Phenotype…
Millions of People in Canada Are Finding AI-Enabled Support for Mental Health Effective Amid Ongoing Questions Around Trust.
New national polling that is the first of its kind in Canada reveals a gap between the rapid adoption of AI tools for mental health support, effectiveness, and public distrust, pointing to human-centred design as the path forward. The post…
Birmingham trusts launch InterSystems shared patient portal
Birmingham and Solihull Mental Health and Birmingham Community Healthcare NHS Foundation Trusts have launched a shared patient portal.
Evaluating Wearable Devices for Remote Monitoring in Psychosis: Pilot Study Nested Within the CONNECT Cohort Study
Background: Digital remote monitoring technologies, including smartphones and wearables, offer promising avenues for early detection of psychosis relapse. However, selecting devices that are acceptable to participants and produce high-quality data remains challenging. Objective: The aim of this nested pilot study…
Loneliness From the Digital Mental Health Practitioners’ Perspective: Thematic Analysis of Semistructured Interviews
Background: Loneliness is a prevalent concern across the United Kingdom. While validated scales exist to quantify the severity of loneliness across populations, there remains a gap in understanding how loneliness manifests and is addressed within therapeutic practice. Given the associated…
AI Reveals Hidden Brain Lesions in Multiple Sclerosis MRI
Researchers combined AI with multiple image processing methods to reliably measure on existing multiple sclerosis MRI scans cortical lesions strongly implicated in disability and cognitive, which would previously have remained undetected. The post AI Reveals Hidden Brain Lesions in Multiple…
STAT+: Compass says depression drug has long-lasting benefits
Vertex makes its largest-ever deal, skyrocketing health insurance costs, and more biotech news from The Readout