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808 results

Human Ventral Tegmental Local Field Potentials in Treatment-Resistant Depression and Obsessive-Compulsive Disorder

The ventral tegmental area (VTA) is a key node within the limbic circuitry. Through dense dopaminergic, glutamatergic, and GABAergic projections, the VTA forms reciprocal loops with prefrontal and limbic cortices that are consistently implicated in major depressive disorder (MDD) and…

Tags: Academic research, Depression, Medication, Mental health, Mood and emotional regulation, OCD, Sexual drive and regulation

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Sociodemographic factors, anxiety and attitudes toward generative artificial intelligence among nurses

BackgroundAlthough generative artificial intelligence offers substantial potential benefits in healthcare, negative attitudes and elevated anxiety among nurses may hinder its effective integration into clinical practice. Evidence regarding the psychological impact of generative artificial intelligence on nurses remains limited.ObjectiveThis study examined…

Tags: Academic research, Anxiety, Healthcare provider

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Multimodal Depression Detection Through Conversational Interactions with an Emotion-Aware Social Robot: Pilot Study

Background: Depression affects more than 300 million people worldwide and is a leading contributor to the global disease burden. Traditional diagnostic methods, such as structured clinical interviews, are reliable but impractical for frequent or large-scale screening. Self-report tools like the…

Tags: Academic research, Depression, Mental health, Mood and emotional regulation

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Enhancing Sleep and Mental Health: Longitudinal, Observational, Real-World Study From a Digital Mental Health Platform

Background: Poor sleep is closely linked to mental health challenges and workplace burnout. Mental health and workplace stressors can impair sleep, while good sleep quality supports cognitive and emotional resources to cope with daily challenges. Despite positive outcomes of maintaining…

Tags: Academic research, Anxiety, Depression, Mental health, Mood and emotional regulation, Psychoeducation program, Sleep and arousal regulation

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The Effectiveness and Mechanisms of Action of App-Based Interventions for Improving Mental Health and Workplace Well-Being: Randomized Controlled Trial

Background: Depression is the most common mental health disorder worldwide and frequently leads to workplace absence. As face-to-face treatment can be difficult to access, app-based interventions are a popular solution, although their effectiveness in working populations and their mechanisms of…

Tags: Anxiety, CBT, Cognitive focus and executive control, Depression, Health app, Mental health, Mood and emotional regulation

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Emotional Training via Telerehabilitation After Surgical Treatment for Facial Palsy: Prospective, Assessor-Blinded, 2-Arm Pilot Cohort Study

Background: Peripheral facial nerve palsy is a debilitating condition that may necessitate surgical intervention. Although motor rehabilitation is considered essential, the most effective approach has not yet been determined. Objective: This study aimed to evaluate the feasibility and effectiveness of…

Tags: Academic research, Anxiety, Healthcare provider

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How adolescent cannabis use reshapes the developing brain — a systematic review

Background and hypothesisCannabis use initiation during adolescence has increased globally, raising concerns about neurodevelopmental consequences during this critical period when the brain undergoes extensive remodeling in cannabinoid receptor-rich regions.Study designThis systematic review examines neurodevelopmental consequences of adolescent cannabis use, focusing…

Tags: Academic research, Fear and threat response, Mental health, Substance abuse, Substance use, United Kingdom

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Milnacipran continuation during pregnancy in a patient with severe post-traumatic stress disorder and psychotic depression: a case report with 3-year pediatric follow-up

Evidence on milnacipran exposure during pregnancy is sparse, complicating treatment decisions when maternal stability depends on this antidepressant. We report a 31-year-old primigravida with severe post-traumatic stress disorder and a severe major depressive episode with psychotic features in the context…

Tags: Depression, Dissociation and identity integration, Medication, Mood and emotional regulation, PTSD

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Electrophysiological and morphological alteration in the visual pathway of children with attention-deficit/hyperactivity disorder

IntroductionAttention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental disorders in children. Optical Coherence Tomography (OCT) and Visual evoked potentials (VEP) are common non-invasive diagnostic techniques. Researchers can use these techniques to identify possible biomarkers and explore the neurodevelopmental…

Tags: Academic research, ADHD, Biomarker, Cognitive focus and executive control, Mental health

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Oxytocin Plus Self-compassion Training in Borderline Personality Disorder

Conditions: Self-compassion Training (SCT) Plus Intranasal Oxytocin; Self-compassion Training (SCT) Plus Intranasal Placebo Interventions: Drug: Intranasal Oxytocin (IN-OXT); Drug: Intranasal Placebo; Behavioral: Self-Compassion Training (SCT) Sponsors: Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau Recruiting

Tags: BPD, Clinical trial, Healthcare provider, Sexual drive and regulation, Social and attachment drive

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Adapted RPM-08 for Substance Use Disorder in Pakistan

Conditions: Substance Use Disorder (SUD); Drug Abuse; Relapse Interventions: Behavioral: Adapted Relapse Prevention Module (RPM-08); Other: Treatment as Usual (TAU) Sponsors: Universiti Sains Malaysia Completed

Tags: Clinical trial, Substance abuse, Substance use

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Medication Treatment for Tics and Tourette’s

There are several kinds of medication than can help kids with Tourette’s or another tic disorder. But it’s important to note that not all kids who develop tics need treatment. Tics are very common. They often go away on their…

Tags: Academic research, ADHD, Medication, Mood and emotional regulation, Motor and impulse regulation, Tic & Tourette

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Associations of psychological distress, gaming motives and internet gaming disorder in adolescents: a network analysis

Background and objectiveThe rapid popularization of the Internet among Chinese adolescents has resulted in the emergence of a public major concern known as Internet Gaming Disorder (IGD). As demonstrated by previous studies, an association has been demonstrated among emotional distress,…

Tags: Academic research, Anxiety, Depression, Mood and emotional regulation, Reality testing and perceptual stability

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