The dual-burden of professional and academic stress: a cross-sectional mapping of mental health status and coping efficacy among postgraduate students in Nairobi, Kenya

BackgroundPostgraduate students face a dual burden of intense academic rigour and professional responsibilities, a dynamic particularly pronounced in growing economic hubs such as Nairobi, Kenya. While global literature highlights rising psychological distress in higher education, there is limited evidence on how specific coping mechanisms mediate mental health outcomes among postgraduates at private African universities. Understanding these dynamics is critical for institutional psychosocial support systems.ObjectivesThis study aimed to assess the mental health status (depression, anxiety, and stress) of postgraduate students at Strathmore University. Grounded in Lazarus and Folkman’s Transactional Model of Stress and Coping Mechanisms.MethodsAdopting a quantitative cross-sectional descriptive design, data were collected from 242 actively enrolled postgraduate students using a random stratified sampling technique. Mental health status was measured using the Depression, Anxiety, and Stress Scale (DASS-21), and coping mechanisms were evaluated via the Coping Orientation to Problems Experienced (COPE) inventory. Data analysis utilised descriptive statistics, Spearman’s rank correlation, and multiple linear regression models.FindingsResults indicated significant psychological strain, with participants reporting difficulty winding down and high levels of anticipatory anxiety (DASS means ranged from 2.23/to 2.73 on a scale of 0-3. Regression analysis showed that coping strategies accounted for 40.2% of the variation in mental health. Notably, emotion-focused coping (β = 0.307, p <.001) and avoidant coping (β = 0.344, p <.001) had significant positive effects on mental well-being in this context. Conversely, problem-focused coping (β = -0.189, p = .002) had a significant negative effect, suggesting that direct action-oriented strategies may exacerbate distress for students facing stressors beyond their immediate control.ConclusionThe study finds that postgraduate mental health is profoundly influenced by the “plasticity” of coping strategies. While active problem-solving is traditionally encouraged, for the Kenyan postgraduate master’s student, adaptive emotion-focused and strategic avoidant strategies currently offer greater psychological relief. Universities must move from generic support to “fit-for-purpose” interventions that destigmatise mental health services and promote adaptive emotional regulation to ensure academic and professional success.

RESCUE- expected usefulness and willingness to participate in a trauma-informed group intervention for coping with traumatic work experiences in the emergency medical services

Emergency Medical Services personnel (EMS) are confronted with potentially highly stressful and traumatic occupational experiences, placing them at high-risk for mental disorders. Avoidant coping mechanisms, internalized and occupational stigma not only impede disclosure of and processing the incident-related stress but also weaken the overall resilience of the EMS. Effective interventions are needed that operate both at the individual and group level. The aim of this study was to investigate the expected usefulness and willingness to participate in a trauma-informed intervention (Facts derived from Narrative Exposure Therapy, NETfacts). A total of 256 German EMS (67.19% men, 32.81% women) participated in the online survey. We assessed the expected usefulness and willingness to participate in NETfacts, critical incident-related stress (EMS Critical Incident Inventory EMS-CII), burnout symptoms (Professional Quality of Life ProQOL), age and work experience. Overall, about half of the EMS expected NETfacts to be at least somewhat useful, and reported a generally willingness to participate. Expected usefulness was neither associated with critical incident-related stress nor burnout symptoms. Younger participants (<35 years) showed a generally higher willingness to participate than older participants. However, the willingness is across both age groups positively associated with higher levels of critical incident-related stress. Nevertheless, burnout symptoms and the willingness are negatively associated among participants age 35 and older, while remaining stable among their younger colleagues. Early, trauma-informed and age-sensitive prevention programs are needed to mitigate the adverse effects of critical incidents among EMS. Our study presents EMS preferred circumstances to enhance employees’ uptake of such a program.

Case Report: Recurrent pathogenic mutation c.110G>A in DHDDS gene

Recent studies have demonstrated the close association of mutations in the dehydrodolichyl diphosphate synthase (DHDDS) gene with neurodevelopmental disorders and the onset of epilepsy. This report describes a female patient harboring a de novo heterozygous variant c.110G>A (p.Arg37His) in the DHDDS gene, characterized by childhood-onset myoclonus-like movement disorder (at age 6) and late-onset epilepsy (at age 17). The movement disorder was remarkably improved through the levetiracetam+ clonazepam+ haloperidol triple therapy, and epileptic seizures were also effectively controlled. A retrospective analysis of 59 epilepsy patients with DHDDS gene variants revealed significant clinical heterogeneity in disease phenotypes caused by DHDDS mutations. Epilepsy was identified as the predominant symptom, commonly accompanied by movement disorders and varying degrees of intellectual disability. Furthermore, while pathogenic mutations in DHDDS tend to be relatively clustered, no definitive genotype-phenotype correlation has been established. This study highlights the clinical manifestations, imaging features, treatment experiences, and genetic testing results through case reports and literature review, thereby providing crucial references for the clinical diagnosis, treatment, and further research of such diseases.