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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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Building a Science-Driven Business: How National Institutes of Health Funding Enabled an Evidence-Based Approach to Maternal Mental Health Innovation
The digital mental health (DMH) industry has grown drastically over the last decade; yet, many DMH products have failed to demonstrate meaningful clinical outcomes, in large part due to lack of scientific evidence. This viewpoint paper highlights an example of…
Expected Competencies and Personal Attributes of Digital Health Navigators to Support Digital Mental Health Care: Focus Group and Interview Study With Patients and Health Care Professionals
Background: Digital mental health apps (DMHAs), and in particular digital therapeutics (DTx), offer promising opportunities to support mental health care. However, their effective use in outpatient settings in Germany remains limited. To overcome this gap, the role of digital health…
How to De-Escalate an Autistic Meltdown
A common misconception about tantrums and meltdowns is that they’re interchangeable. But while they share some similarities in their initial expression — crying, screaming, door slamming, harsh words — they’re actually quite different. Dealing with a meltdown requires a more…
Auditory processing and communication in autism: exploring verbal abilities and vocal affective cues
This study examined the role of auditory processing in autism spectrum disorder, focusing on its association with verbal and non-verbal vocal communication skills in children and adolescents. A total of 97 English-speaking autistic participants (ages 7.9–17.4 years, mean = 12.3)…
Appearance-related attentional bias is associated with dysmorphic appearance concern in individuals with jaw deformity: an eye-tracking study
IntroductionAppearance-related attentional bias has been body dysmorphic disorder (BDD) and in individuals with elevated concern; however, it remains unclear whether similar attentional are observed in individuals with objectively verifiable jaw deformities. Appearance-related attentional bias has been observed across clinical populations…
Cyclothymic and anxious affective temperament in perinatal depression: findings from an exploratory cross-sectional study
IntroductionThe perinatal period represents a vulnerable period in which women may experience high psychic distress due to psychological, biological and social changes. The prevalence of perinatal depression (PND) is estimated around 15%-20% during pregnancy and 16%-18% after childbirth. Although several…
Growth, Empowerment, and Mindfulness (GEM): A Mindfulness-based Intervention to Address Mental Health in Young Adults With Early Life Adversity
Conditions: Anxiety; Depression Interventions: Behavioral: Growth, Empowerment, and Mindfulness (GEM) Sponsors: Brown University Recruiting
Autism Spectrum Disorder (ASD) Neurodevelopmental Disorder With Issues Social Behavior, Communication Issues, GI Dysfunction. Study is Multimodal Interventions Targeting These Pathways With cSVF, Stored MSCs, FMT and Diet Modification. Role of Autoimmunity, Gut-brain Issues, & Issues Examined.
Conditions: Autism Spectrum Disorder; Autism Interventions: Procedure: Autologous MSC isolation, concentration, and cryopreservation of adult mesenchymal stem cells; Dietary Supplement: Fecal Biomicrome Transplantation (FMT); Dietary Supplement: Ketogenic RESET Diet Protocol; Behavioral: Trial combines use of cSVF and MSCs (cryopres) with…
Multicomponent Intervention to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment
Conditions: Mild Cognitive Impairment (MCI) Interventions: Behavioral: Cognitive stimulation; Behavioral: Lifestyle psychoeducation; Behavioral: Sham cognitive stimulation; Behavioral: Sham Lifestyle Psychoeducation Sponsors: City University of Hong Kong Not yet recruiting
Effectiveness of a Fully Automated Mobile Therapeutic Versus a General Chatbot in Reducing Depression and Anxiety and Improving Well-Being: Feasibility Randomized Controlled Trial
Background: Given the increasing prevalence of depression and anxiety disorders and enduring barriers to care, there is a critical need for alternative treatment options. Generative artificial intelligence (AI) chatbots show promise for increasing access to mental health care, though more…
Fifth Annual SoFi Child Mind Institute Golf Invitational Raises $630,000 to Support Youth Mental Health
On April 20, the Child Mind Institute and SoFi held its fifth annual Golf Invitational at the Olympic Club in San Francisco. The event raised $630,000 to support the organization’s mission to transform the lives of children and families struggling…
Oral administration of kratom leaf extract alleviates anxiety-like behavior, urinary bladder pain, voiding dysfunction, and bladder hypercontractility via attenuating muscarinic receptor response in male mice exposed to chronic water avoidance stress
Psychological stress causes and deteriorates interstitial cystitis/painful bladder syndrome with urinary frequency, incontinence, bladder pain and urgency. The major alkaloid of kratom (Mitragyna speciosa), mitragynine, shows analgesic, anxiolytic, and smooth muscle relaxant effects. However, the effects of kratom leaf extract…
Tideglusib improves novel object recognition memory in the preclinical DBA/2J mdx mouse model of Duchenne muscular dystrophy
IntroductionDuchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular disorder characterized by progressive muscle wasting. Approximately 1 in 3 DMD patients experience cognitive dysfunction, with research suggesting an Alzheimer’s disease (AD)-like pathology. We have previously shown that treatment with the…
The temporal stability of core symptoms of social media addiction and their comorbidity with anxiety and depression in adolescents: a longitudinal network analysis
IntroductionSocial media addiction (SMA) is often comorbid with anxiety and depression. This study examined the temporal stability of core SMA symptoms and the bridging symptoms with anxiety and depression.MethodsA total of 1,240 adolescents (179 males, 1,061 females; mean age =…
Psychometric properties of Lithuanian translation of the self-report version of the Liebowitz social anxiety scale in young adult sample
BackgroundSocial anxiety disorder starts in adolescence or young adulthood and may have damaging effects on psychosocial development of the individual. Any intervention starts from assessment and the Liebowitz social anxiety scale with later developed self-report version is a valuable tool…
Group CBT targeting hostile attribution bias in adolescents and young adults with ASD traits
BackgroundAdolescence is characterized by heightened self-consciousness and sensitivity to social evaluations. During this period, hostile attribution bias—interpreting ambiguous social cues as hostile—can lower quality of life (QOL) and contribute to future mental health problems. Adolescents with autism spectrum disorder (ASD)…
Effectiveness and mechanisms of Intensive Short-Term Dynamic Psychotherapy for treatment-resistant depression: a reanalysis of a randomized controlled trial
IntroductionIntensive Short-Term Dynamic Psychotherapy has shown promising effects for treatment-resistant depression, but it remains unclear whether its hypothesized mechanisms — reducing emotional repression, negative affect, and psychological distress — actually mediate treatment outcomes.MethodsWe reanalyzed publicly available data from a randomized…
Carea adds miscarriage support feature to maternal health app
Carea has launched a digital support tool within its app to provide guidance and mental health support for women following pregnancy loss.
THE EFFECTS OF AN ONLINE FAMILY PSYCHOEDUCATION PROGRAM ON EXPRESSED EMOTION OF FAMILY MEMBERS AND MEDICATION ADHERENCE OF PATIENTS WITH FIRST-EPISODE SCHIZOPHRENIA
Conditions: First- Episode Schizophrenia Interventions: Behavioral: Mobile based family psychoeducation program Sponsors: Mahidol University Completed
Internet addiction among nursing students: application of latent profile analysis and network analysis
BackgroundInternet addiction is widely reported and heterogeneous among nursing students. However, variable-centered approaches may not fully capture profile differences and core symptom patterns, potentially limiting precise interventions. Therefore, identifying distinct profiles and key symptoms is important for informing effective prevention.ObjectiveThis…