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ARIA funding
We’re proud to share that Relatix Bio has applied for funding from the UK’s Advanced Research and Invention Agency (ARIA) under their Trust Everything, Everywhere programme. This initiative explores how trust can be built across the digital and physical worlds,…
Relatix Bio’s Vision for a Better Tomorrow
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Empathic Disorders: From Diagnosis to Care
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GABA-Based Target for Alzheimer’s Therapy Identified
Modulation of gamma-aminobutyric acid (GABA) signaling can restore disrupted neural balance and improve memory-related function in AD disease models. The post GABA-Based Target for Alzheimer’s Therapy Identified appeared first on Inside Precision Medicine.
Number of children and maternal mental health in the context of China’s fertility policy transition: the moderating effect of employment status and the mediating effect of family environment
BackgroundHaving more children may be detrimental to maternal mental health during China’s ongoing fertility policy transition. However, under what circumstances and how number of children could be associated with maternal mental health remains understudied in China. This study examined the…
Effect of a nursing-based information–motivation–behavioral model on older patients with type 2 diabetes mellitus
BackgroundOlder patients with type 2 diabetes mellitus (T2DM) frequently encounter challenges, including a diminished capacity for self-management, a high prevalence of negative emotions, and cognitive decline and physiological changes attributable to long-term disease burden, leading to compromised glycemic control and…
Coping under pressure: police-specific stressors and mental health in Catalonia police forces
IntroductionPolice officers are exposed to elevated psychological risks due to both operational and organizational stressors. Additionally, police officers tend to resort to avoidant coping strategies, which exacerbate poor mental health outcomes, such as burnout and PTSD.MethodsThis study aims to examine…
Iron dyshomeostasis in neuropsychiatric disorders
Iron is an indispensable element for the normal physiological function of the brain. In terms of neuronal metabolism, iron is involved in multiple critical biological processes such as oxygen transport, energy metabolism, DNA synthesis, neurotransmitter synthesis and myelin formation. Maintaining…
Exposure to negative physical and social factors accelerates brain aging
Nature Medicine, Published online: 21 April 2026; doi:10.1038/s41591-026-04348-zIn a study that included 18,701 people from 34 countries, 73 aggregated physical and social exposomes exhibited nonlinear, synergistic effects that accelerated brain aging. In some cases, these effects were comparable to or…
Photobiomodulation on Core Symptoms of Autism
Conditions: Autism Interventions: Device: Photobiomodulation Sponsors: Suez University Not yet recruiting
MDMA Assisted Therapy for BN
Conditions: Bulimia Nervosa Interventions: Drug: MDMA-AT; Drug: MDMA-AT-BN; Behavioral: Standard Treatment (ST) Sponsors: Icahn School of Medicine at Mount Sinai Not yet recruiting
Adapting Behavioral Interventions for Dementia to Address NCDs and Mental Health
Conditions: Mental Health; Non Communicable Diseases; Dementia Interventions: Behavioral: BECOME-D Intervention Sponsors: Possible; University of California, San Francisco; National Institute of Mental Health (NIMH); Ministry of Health and Population, Nepal Completed
Access to Technology-Mediated Community Mental Health Care Among Low-Socioeconomic Status Consumers With Serious Mental Illness: Qualitative Study
Background: Access to mental health care is critical for the effective management of serious mental illness (SMI), but consumers with low socioeconomic status (SES) have lower rates of service usage and worse retention in care. Digital technologies are often lauded…
Opportunities for Digital Health to Support Early Psychosis Care in Ghana: Qualitative Study Among Patients, Caregivers, and Clinicians
Background: Youth experiencing early psychosis in West Africa often face delays in accessing evidence-based treatment. Digital mental health interventions may offer an acceptable and scalable approach to improve access to early psychosis care in West Africa; however, few data exist…
Popular Online Content as a Treatment-as-Usual Control in Digital Mental Health Intervention Trials: Secondary Analysis of Two Online Randomized Controlled Trials With Repeated Measures
Background: Treatment-as-usual (TAU) conditions are intended to reflect the support typically received in routine treatment settings. For digital mental health interventions (DMHIs) delivered online, TAU conditions should reflect the usual patterns of online help-seeking. The lack of ecologically valid TAU…
Altered static and dynamic regional homogeneity in basal ganglia–thalamocortical circuits and their association with neuropsychiatric manifestations in Wilson’s disease
PurposeWilson’s disease (WD) is an autosomal recessive disorder caused by ATP7B mutations, resulting in impaired copper metabolism and progressive neuropsychiatric manifestations. This study investigated spatiotemporal alterations in regional brain activity using static and dynamic resting-state fMRI with regional homogeneity (ReHo),…
Machine learning for oral frailty factors in hospitalized schizophrenia patients: two-stage feature selection and SHAP analysis
BackgroundLong-term hospitalized patients with schizophrenia (SZ) often experience significant oral health problems, and oral frailty (OF) can further exacerbate the decline in their quality of life. However, the status and key influencing factors contributing to OF in this population remain…
Postmarketing surveillance of elobixibat for patients with chronic constipation and concomitant schizophrenia or depression in Japan
BackgroundLittle is known about the optimal treatment for constipation in patients with schizophrenia or depression. Elobixibat is a laxative with a novel mechanism of action that inhibits the ileal bile acid transporter, acting as both an osmotic and a stimulant…
Twelve-month outcomes and comparative costs of internet-delivered psychodynamic therapy versus cognitive-behavioral therapy for adolescent depression: a randomized controlled trial
IntroductionAdolescent depression poses a major public health concern with substantial clinical and societal implications. Both internet-delivered cognitive behavioural therapy (ICBT) and internet-delivered psychodynamic therapy (IPDT) have shown efficacy, but questions remain regarding long-term efficacy and cost-effectiveness. The present study presents…
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Conditions: Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group; Diagnosis of ADHD Using the KSADS-PL for the ADHD Group; Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group; All Participants Were…
A Toolkit to Improve Mental Health Treatment for Autistic Individuals
Conditions: Autism; Mental Health Conditions Interventions: Behavioral: Enhanced Psychotherapy; Behavioral: Treatment as Usual (TAU) Sponsors: Florida International University; Organization for Autism Research Not yet recruiting
Oral Microecology in Children With Autism
Conditions: Autism; Caries,Dental Sponsors: The Dental Hospital of Zhejiang University School of Medicine Completed