The UK’s generational tobacco ban might not work. I’m supporting it anyway.

As the parent of two little girls, I often think about how their childhood is different from mine. The seven-year-old is learning about AI at school. The five-year-old is given internet-based homework every week. And they are both absolutely repulsed by the idea of smoking.

That was not the prevailing sentiment when I was young. My parents smoked. The customers at our family’s restaurant smoked. Cartoon characters smoked. My friends and I would buy little cigarette-box-shaped packets of sugary white sticks and pretend to smoke in the playground. Smoking was a central part of our culture.

Which is why the UK’s recent passing of a generational sales ban on tobacco products feels like such a big deal. As part of the Tobacco and Vapes Act 2026, retailers are prohibited from selling tobacco products to anyone born after January 1, 2009, in perpetuity. It doesn’t matter when those people turn 18—or 38 or 68, for that matter. It will always be illegal to sell to anyone born after that date.

This is what’s described as an “endgame” approach. While many tobacco control strategies—such as taxation or gory imagery—aim to reduce consumption, policies like the UK’s are designed to eliminate it entirely. It’s a new approach, and no one knows whether it will work.

The Maldives was the first country to implement a generational smoking ban, in November last year. It’s too soon to say how that has panned out.

Nor do we know if these laws will even last. In 2022, New Zealand passed a similar generational sales ban as part of a broader anti-smoking law. But it was never enacted—the law was repealed by a new government in February 2024.

In the UK, both major parties support the ban. But Nigel Farage, whose right-wing party has seen a recent surge in support, has promised that “the generational smoking ban will not last long if Reform gets the chance to start rebuilding our mismanaged country.”

Chris Bostic, an attorney and former policy director for the advocacy group Action on Smoking and Health, says he and his colleagues began promoting the idea of a generational ban in the United States 11 years ago. Back then, they struggled to win support, even from major health charities. “People said we were crazy … [and] that this was impossible,” he says. Opponents argued that bans would infringe on personal freedoms.

“The public health argument is: Well, what about freedom from addiction?” says Britta Matthes, a tobacco control researcher at the University of Bath in the UK. Most people who smoke began when they were teenagers, want to quit, and wish they’d never started. Tobacco is arguably the most harmful consumer product of all time. It will kill half its users who don’t quit, according to the World Health Organization.

It also kills people who don’t smoke. Of the 7 million who die from tobacco every year, 1.6 million are nonsmokers who were exposed to secondhand smoke, according to the WHO.

Generational sales bans are a long-term strategy that will only protect future smokers. Most experts agree that people who already smoke should be a main consideration for any policy, and that a multipronged approach is probably the best way to go. Janet Hoek at the University of Otago, who has explored tobacco control policies in New Zealand, believes that enforcing very low limits on nicotine levels and banning filters—an environmental scourge that does not make smoking safer, as many people believe—might be a “powerful combination,” for example.

But preventing teenagers from starting to smoke in the first place is an enticing prospect, even among the majority of people who smoke. And it’s starting to look a lot less radical.

The US has quietly been making progress on a smaller scale. Since 2021, Brookline, a town in the Boston area, has banned the sale of tobacco products to anyone born after January 1, 2000. The idea has spread. Today there are 23 towns in Massachusetts with similar bans, says Bostic. Nine towns across Minnesota, New York, and California have implemented other endgame policies.

The UK law has normalized the idea more than ever, he adds. His colleagues are already fielding calls from health agencies around the world. “People [are] saying, Wow I can’t believe the UK just did this—can we do this here?” he says.

Norms change. Like many other millennials, I vividly remember my first night out after a ban on indoor smoking took effect. My clothes didn’t stink! My hair still felt clean! And my throat wasn’t scratchy the next morning! Now that’s just normal. I hope a tobacco-free world can be the new normal for my kids.

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The relationship between mobile phone addiction and depression, anxiety among Chinese college students: the mediating role of friendship quality and the moderating effect of preference for solitude

BackgroundThe university stage represents a critical period for the development of individual mental health. Mobile phone addiction is closely linked to depression and anxiety among college students, and both friendship quality and preference for solitude are tightly associated with college students’ mobile phone addiction and emotional health. Therefore, this study aimed to investigate the relationships and internal mechanisms among mobile phone addiction, friendship quality, preference for solitude, depression and anxiety in college students.MethodsA total of 1083 Chinese college students (58.2% female; mean age = 19.87 ± 1.692 years) were included as participants. Data were collected using the Mobile Phone Addiction Index, Friendship Quality Questionnaire, Preference for Solitude Questionnaire, and Depression Anxiety Stress Scale. Data processing and analyses were conducted using SPSS 26.0 and the PROCESS macro.Results(1) Mobile phone addiction was significantly negatively correlated with friendship quality, and significantly positively correlated with both depression and anxiety; friendship quality was significantly negatively correlated with depression and anxiety; preference for solitude was significantly positively correlated with depression and anxiety. (2) Mobile phone addiction not only directly and positively predicted depression and anxiety among college students, but also predicted depression and anxiety through the mediating role of friendship quality. (3) The direct effect of mobile phone addiction on depression and the mediating effect of friendship quality in the relationships between mobile phone addiction and depression/anxiety were both moderated by preference for solitude, whereas the moderating effect of preference for solitude on the association between mobile phone addiction and anxiety was not significant.ConclusionFriendship quality serves as an important mediating pathway between mobile phone addiction and depressive and anxiety symptoms among Chinese college students. Preference for solitude may amplify the associations of mobile phone addiction with poorer friendship quality and elevated depressive symptoms.

Expedited Transition to Digital Delivery of Recovery Support Services Due to the COVID-19 Pandemic: Mixed Methods Needs Assessment

Background: Recovery support services (RSS) are an evidence-based approach to support recovery from substance use disorders, most often composed of peer-to-peer support, referrals to housing, job training, and other forms of prosocial engagement and activities. During the COVID-19 pandemic, RSS providers quickly converted in-person services to digital delivery to avoid disruption. It is unclear if this rapid conversion impacted the delivery of services or if this delivery model could enhance RSS reach and uptake more generally by extending the reach of RSS providers and offering an alternative delivery method and access point. Objective: The goal of this study was to identify how RSS providers in Texas adapted their services for digital delivery and to what extent, if at all, technology limitations (eg, lack of digital infrastructure) were present. Methods: We conducted an electronic survey of 85 RSS providers, assessing their current capacity and methods for the digital recovery support service (D-RSS), followed by semistructured online interviews with a subset of 20 respondents. Results: Most survey respondents (74/85, 87.1%) used D-RSS, though they used many dated technologies, devices, and platforms for service delivery. Many respondents indicated that they use Zoom (Zoom Video Communications) videoconferencing to communicate with participants; however, providers also indicated that they must use several different technology platforms to accomplish their service delivery goals. Four main themes emerged from the interviews: (1) the impact of the COVID-19 pandemic on RSS, (2) barriers and facilitators to technology-delivered D-RSS, (3) awareness and expectations regarding the use of D-RSS, and (4) training needs to deliver D-RSS. Conclusions: RSS organizations have access to technology for D-RSS; however, the technology is often outdated. Because the pandemic required a rapid and unexpected shift to D-RSS to maintain and potentially expand access during a public health emergency, providers desire guidance for training staff and participants on how to best use technology. A subset of providers endorsed the potential of a unified platform for D-RSS delivery, especially for data capture. Most barriers to D-RSS identified by our respondents may be addressable through the streamlined deployment of technology resources, rigorous training and onboarding programs in best practices for providers and participants, and tailored implementation strategies for varying local contexts.
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Catheter-Based OCT Imaging Shows Promise for Noninvasive Endometrial Cancer Diagnosis

A research team at Washington University in St. Louis has developed a catheter-based optical imaging method that could be used as an “optical biopsy” for detecting endometrial cancer and its precancerous lesions. The approach, described in the journal npj Imaging, uses three-dimensional optical coherence tomography (OCT) imaging combined with a machine learning algorithm which examines and analyzes the entire endometrial cavity to identify tissue changes associated with endometrial intraepithelial neoplasia (EIN) and endometrial cancer.

“Current endometrial biopsy practice has an estimated false-negative rate of about 10% (approximately 90% sensitivity), largely due to sampling limitations and interpretive variability,” said senior investigator Quing Zhu, PhD, a professor of engineering at Washington University. “With our three-dimensional OCT imaging system combined with machine learning, we can image the entire endometrial cavity in two to three seconds and may have a potential to achieve higher sensitivity than random biopsy sampling.”

Endometrial cancer is the most common gynecologic malignancy in the United States, with estimated 69,000 cases projected to be diagnosed in 2025. As with most cancers, early detection has a significant impact on treatment outcomes with five-year survival rates between 80% and 90% when it is diagnosed at stage I.

Existing diagnostic tools have limitations that can impact early and accurate diagnosis. For instance, transvaginal ultrasound is ineffective for early EC, while endometrial biopsy has a 10% false-negative rate due to sampling and interpretive variability.” Although hysteroscopy allows direct visualization of the uterine cavity, it does not provide information about subsurface tissue architecture.

In an interview with Inside Precision Medicine, Zhu said the most widely used diagnostic approaches can miss cancers or depend heavily on operator skill. She noted that the low resolution of transvaginal ultrasound limits detection of early disease, while operative hysteroscopy requires cervical dilation and carries procedural risks. Endometrial biopsy, she added, can miss cancers that occupy less than half of the endometrial cavity surface.

The new approach developed by Zhu and team uses OCT, a light-based imaging technology that creates high-resolution cross-sectional images of tissue. This imaging method uses low-coherence interferometry to measure the echo time delay and intensity of backscattered light, producing real-time images of tissue microstructure with micrometer-scale resolution with tissues penetration depths of approximately one to two millimeters.

To create a method to comprehensively image the endometrium the WashU team developed a custom 3.1-millimeter catheter. Zhu said that the catheter rotates within the endometrial cavity at roughly 600 revolutions per minute while being pulled back automatically at a constant speed. Depending on uterine size, a 3- to 5-centimeter segment of the cavity can be imaged in approximately two to three minutes. The resulting volumetric scans provide three-dimensional views of tissue structure and optical properties throughout the cavity. The team then applied computational analysis to identify functional, structural, and radiomic features based on OCT intensity and scattering images.

To test this OCT/machine learning approach, the researchers evaluated the technology on 57 freshly excised hysterectomy specimens representing a range of conditions, including normal endometrium, benign abnormalities, EIN, and endometrial cancer. OCT identified 34 specimens that contained either high-risk precancerous lesions or early-stage cancers.

The OCT images revealed differences among normal endometrium, benign endometrium, high-risk precancerous lesions, and cancers at different stages. This new method attained an exploratory sensitivity of 94% and specificity of 87%. A cross-validated logistic regression classifier produced sensitivity of 91% and specificity of 83%.

“These findings support catheter-based 3D OCT as a promising noninvasive optical biopsy approach to improve detection of endometrial cancer,” the researchers wrote in the abstract.

The work builds on earlier investigations of OCT in endometrial disease. Previous research had shown that OCT could distinguish endometrial pathologies, but in those studies the imaging was slow or limited to two-dimensional analysis. “This study is the first to combine catheter-based 3D OCT imaging with functional, structural and radiomic feature analysis to assess the endometrial cavity,” the researchers wrote.

Researchers believe the technology could improve patient care by reducing dependence on repeated tissue biopsies. In the introduction, they wrote that “a real-time, noninvasive, high-resolution modality for subsurface imaging could improve diagnostic accuracy, reduce unnecessary biopsies, and support fertility-sparing management.” Such a tool could be particularly useful for women undergoing serial monitoring while receiving hormone-based treatment.

The investigators describe the method as an optical biopsy because it provides diagnostic information without requiring removal of tissue. “Unlike traditional tissue biopsy, it does not require painful physical tissue samples,” Zhu told Inside Precision Medicine.

The technology is still in an early stage of development. Zhu said future development will require a forward-viewing catheter to improve imaging of the uterine fundus and developing methods for faster data acquisition.

Zhu is now looking to secure funding and begin studies in patients to establish in vivo feasibility and to eventually move the technology into clinical trials.

The post Catheter-Based OCT Imaging Shows Promise for Noninvasive Endometrial Cancer Diagnosis appeared first on Inside Precision Medicine.

The Download: introducing the Engineering issue

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology.

Introducing: the Engineering issue

We can’t fix everything, but we can be ambitious. We can take on the challenge of making the world better through human ingenuity. That’s what the new Engineering issue of MIT Technology Review is all about. 

Sometimes the challenges we face are giant, like tunneling beneath the seafloor. Some exist at the nanoscale, as with a new ASML machine powering the future of chipmaking. Others represent problems at a planetary scale and in truly unknown territory, like replicating a volcano’s mechanism to cool the Earth on purpose.

These incredible engineering stories show we can come together to get to work and, when the smoke clears, find we’ve made real progress. Subscribe now to read all of them—and more—in the full print issue.

Stripe, Anthropic, and OpenAI are backing an effort to stop respiratory infections

The common cold comes for us all—often more than once a year. And there is no way to prevent it. The best you can do is take vitamin C and stay away from people with the sniffles.

Now, the payment company Stripe is funding a new $500-million nonprofit aiming to prevent both the common cold and the flu. Its eventual goal is to get rid of respiratory viruses altogether.

Anthropic, OpenAI, and Bill Gates have also backed the venture, which will investigate whether modern technologies can counter the common cold and the flu. Dive into the nonprofit’s plans.

—Antonio Regalado

MIT Technology Review Narrated: inside the hunt for the most dangerous asteroid ever

As asteroid 2024 YR4 hurtled toward Earth, astronomers determined that this massive rock posed a higher risk of impact than any object of its size in recorded history. Then, just as quickly as history was made, experts declared that the danger had passed. 

This is the inside story of the network of global scientists who found, followed, planned for, and finally dismissed the most dangerous asteroid ever discovered —all under the tightest of timelines and with the highest of stakes.

—Robin George Andrews

This is our latest story to be turned into an MIT Technology Review Narrated podcast, which we publish each week on Spotify and Apple Podcasts. Just navigate to MIT Technology Review Narrated on either platform, and follow us to get all our new content as it’s released.

The must-reads

I’ve combed the internet to find you today’s most fun/important/scary/fascinating stories about technology.

1 China has taken the US’s crown for the world’s fastest supercomputer 
Shenzhen’s LineShine overtook California’s El Capitan. (Axios)
+ China had not had a machine at the top of the list since 2017. (NYT $)
+ But the supercomputer race isn’t geared for AI work. (Reuters $)

2 Mythos reportedly found flaws in classified US government systems
A US official said Anthropic’s model identified certain vulnerabilities. (AP News)
+ The model has now been suspended over US security concerns. (BBC)
+ The NSA has lost access to Anthropic’s tools in fallout. (Engadget)
+ The feud raises new questions about AI safety. (MIT Technology Review) 

3 A US pilot reported seeing Iranian drones swarm in “jellyfish” formation
Which would represent an alarming advance in Iranian drone capabilities. (CNN)
+ The US is heading toward a drone-filled future. (MIT Technology Review)

4 Mark Zuckerberg directed Meta to create a prediction markets app
It will be similar to Polymarket and Kalshi. (NYT $)
+ But won’t let users wager real money. (The Verge
+ Another new app, Meta Photos, will create media with AI. (Reuters $)

5 SpaceX’s “Starfall” just launched a secretive test flight
The orbital delivery spacecraft blasted off for the first time yesterday. (Axios)
+ It could also support space manufacturing. (New Scientist $)

6 Alibaba has sued the US for being linked to the Chinese military
It wants to be removed from a Pentagon blacklist. (Reuters $)

7 Nvidia’s banned AI chips have doubled in price on China’s black market
The DGX B300 now costs more than $1.1 million. (Financial Times $)

8 Tesla claims a driver “manually overrode self-driving” in a deadly crash
It said the accelerator was pressed “all the way to 100%.” (The Verge $)

9 The US science retreat has created an opportunity for Europe
But questions about funding and innovation remain. (Nature)
+ Trump has dealt many blows to US science. (MIT Technology Review)

10 Meta’s new smart glasses ditch Ray-Bans for Kylie Jenner 
Meta logos and Jenner designs have replaced the Ray-Ban branding. (Wired $)

Quote of the day

“It’s blasphemy against AI if ‌you say it’s a bubble.”

—SoftBank founder and CEO Masayoshi Son tells shareholders that the AI boom is still in its early stages, Reuters reports.

One More Thing

ERIK CARTER


Video games are dividing South Korea

They say StarCraft was the game that changed everything. When the science fiction strategy game arrived in South Korea in 1998, it wasn’t just a hit—it was an awakening.

Out of 11 million copies sold worldwide, 4.5 million were in the country. The game was so popular that it triggered another boom: “PC bangs,” pay-as-you-go gaming cafés.

StarCraft and PC bangs spoke to a generation of young South Koreans boxed in by economic anxiety and rising academic pressures. But they also sparked arguments about game addiction. They’ve led to feuds between government departments—and a national debate over policy.

Read the full story.

—Max S. Kim

We can still have nice things

A place for comfort, fun, and distraction to brighten up your day. (Got any ideas? Drop me a line.)

+ This archive lovingly documents the beautiful design of over 1,700 obsolete objects.
+ Classic TV theme tunes like Hey Arnold! Have been revived in a musician’s marvellous samples.
+ Marvel at the mind-boggling geometry of nature and see how bees perfectly construct honeycombs.
+ Hear the ominous, deeply atmospheric tones of a custom string instrument built inside a plastic drainage pipe.