Tag: Academic research

When I was 18, I skipped my high school graduation and headed to Kuwait. It was 1991, the first Gulf War had just ended, and the country was in complete chaos. There was little to no electricity, aside from generator power. Rubble and unexploded ordnance were everywhere. Massive oil fires lit up the desert and dimmed the sky overhead. Everything had to be rebuilt, and fast. 

I was there to work on that reconstruction, part of an international effort to fix what war had broken. It was the first time I’d ever seen a truly massive engineering project with my own eyes. The challenge was one that had to be addressed on multiple fronts, simultaneously, to get an entire country back up and running. 

Everywhere you looked, there was something to do. I was mostly working with a labor crew to jump on quick fixes to things like windows and doors blown out in the fighting. But there were, of course, bigger jobs too. Most notably, there were those massive fires to put out. The Iraqi army had set hundreds of oil wells ablaze, the majority of which were still spewing soot and oil smoke into the air. On bad days, the sky would remain dark all day, and the air would burn your eyes and hurt your throat.

It was so apocalyptic that none other than Carl Sagan warned of massive environmental consequences. If smoke from the oil fires reached the stratosphere, he predicted, the result could be akin to the 1815 explosion of the Tambora volcano in Indonesia, which triggered what’s known as “the year without a summer”; global temperatures dropped between 0.4 and 0.7 °C, and crops failed around the world. Fortunately, the plume from Kuwait never made it that high, and although temperatures did decline regionally, there was little effect on a planetary scale. As it turns out, predicting what will or won’t lower global temps is quite hard. (Reader, I am foreshadowing here.) 

Firefighters from companies with monikers like the Red Adair Company or Boots and Coots (as well as less colorfully named outfits, like Bechtel) rushed to Kuwait after the war’s end to figure out how to extinguish the gargantuan blazes and cap the wells. At a hotel in downtown Kuwait City, one of the few places with working phone lines, I would occasionally run into them covered head to toe in black oil and soot. 

Putting out the fires took all sorts of creative thinking. Engineers working in the burning oil fields figured out they could repurpose existing pipelines meant to pump oil out to sea to instead pump water in from the Persian Gulf. One company from Hungary rigged up a firefighting machine called Big Wind by outfitting an old Soviet T-34 tank chassis with two turbines from a MiG-21 fighter jet, each of which could blast 220 gallons of water per second. Sadly, I never got to see it in action (except in the movies). 

Other jobs were less cinematic but no less dire. The retreating Iraqi army had left booby traps all over. They snaked hand grenades into the plumbing (at a facility where I worked, among others). They planted mines everywhere, and those had to be found and removed. Many of them were small plastic “toe poppers” designed not to kill but to maim. Hunting them was a herculean effort. And although it was mostly successful, hundreds of thousands of them, by some estimates, still remain.

Which is to say, we can’t fix everything. But we can be ambitious. We can take on the challenge of making the world better through human ingenuity. 

That’s what the July/August issue of MIT Technology Review is all about. Sometimes the challenges we face are giant, if knowable, like tunneling beneath the seafloor. Some exist at the nanoscale and represent decades of investment and research, as is the case with ASML, a company with the singular ability to produce the machines that make the most advanced computer chips in the world. Others represent problems at a planetary scale and take us into truly unknown territory, like a future where we could engineer the veil of the Tambora volcano to cool the Earth on purpose.

By the end of my 90-day contract in Kuwait, instead of damage everywhere you looked you could see the fruits of a gargantuan international rebuilding effort. The air was not clean, exactly, but inhaling it no longer felt like smoking a pack a day. On the beach, which had been pocked with mines, people swam and splashed at the edge of the gulf. The lights were on. Water ran from the taps. The markets were open. It was a remarkably different place. 

Yes, forces both within and beyond our control will always break things. People will invariably make mistakes, or act out of their own self-interest to the detriment of others. But we can also come together to get to work and, when the smoke clears, find we’ve made real progress. 

What if you could precisely change the genome of a pre-implantation human embryo and then safely use that embryo to try to generate a healthier person? It’s a wild idea, but one that technology over the past decade has steadily made a bit less fantastical, at least practically speaking.

But even as CRISPR gene-editing research has advanced, including exciting work reported in a new preprint on base editing of human embryos from geneticist Dieter Egli’s lab at Columbia, the same tough ethical questions remain.

Read the rest…